Cited 22 times in
Localization of Der f 2 in the gut and faecal pellets of Dermatophagoides farinae
DC Field | Value | Language |
---|---|---|
dc.contributor.author | 용태순 | - |
dc.contributor.author | 정경용 | - |
dc.date.accessioned | 2016-05-16T11:02:11Z | - |
dc.date.available | 2016-05-16T11:02:11Z | - |
dc.date.issued | 2002 | - |
dc.identifier.issn | 0105-4538 | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/143645 | - |
dc.description.abstract | Background: House dust mite derived materials are known to be the most potent agent inducing allergic diseases. Localization of Der f 2 was attempted to specify the sites and concentrations of Der f 2 within the mite, which may indicate the importance of secreted materials and nonexcreted body components as allergen sources. Methods: Serial cryostat sections of embedded live mites and the fecal pellets, collected by brush, were immunoprobed using monoclonal antibody (mAb) 2F38 raised against recombinant (r) Der f 2. Results: Highest concentrations were found in the anterior midgut, implying that this is the site of Der f 2 synthesis and secretion. Digestive material and defecated fecal pellets were also labeled with mAb. Conclusions: Our results show that the major allergen, Der f 2, found in the house dust mite D. farinae is derived from the digestive tract, and is concentrated in the feces. | - |
dc.description.statementOfResponsibility | open | - |
dc.format.extent | 729~731 | - |
dc.relation.isPartOf | ALLERGY | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.rights.uri | https://creativecommons.org/licenses/by-nc-nd/2.0/kr/ | - |
dc.subject.MESH | Allergens/immunology | - |
dc.subject.MESH | Allergens/metabolism* | - |
dc.subject.MESH | Animals | - |
dc.subject.MESH | Antibodies, Monoclonal/metabolism | - |
dc.subject.MESH | Antigens, Dermatophagoides/immunology | - |
dc.subject.MESH | Antigens, Dermatophagoides/metabolism* | - |
dc.subject.MESH | Arthropod Proteins | - |
dc.subject.MESH | Dermatophagoides farinae/immunology* | - |
dc.subject.MESH | Digestive System/metabolism | - |
dc.subject.MESH | Female | - |
dc.subject.MESH | Immunoglobulin G/metabolism | - |
dc.subject.MESH | Immunohistochemistry/methods | - |
dc.subject.MESH | Male | - |
dc.subject.MESH | Mice | - |
dc.subject.MESH | Microscopy, Fluorescence | - |
dc.subject.MESH | Sex Factors | - |
dc.title | Localization of Der f 2 in the gut and faecal pellets of Dermatophagoides farinae | - |
dc.type | Article | - |
dc.contributor.college | College of Medicine (의과대학) | - |
dc.contributor.department | Dept. of Environmental Medical Biology (환경의생물학) | - |
dc.contributor.googleauthor | K. Y. Jeong | - |
dc.contributor.googleauthor | I.Y. Lee | - |
dc.contributor.googleauthor | H.I. Ree | - |
dc.contributor.googleauthor | C.S. Hong | - |
dc.contributor.googleauthor | T.S. Yong | - |
dc.identifier.doi | 10.1034/j.1398-9995.2002.23623.x | - |
dc.admin.author | false | - |
dc.admin.mapping | false | - |
dc.contributor.localId | A02424 | - |
dc.contributor.localId | A03572 | - |
dc.relation.journalcode | J00062 | - |
dc.identifier.eissn | 1398-9995 | - |
dc.identifier.pmid | 17639700 | - |
dc.identifier.url | http://onlinelibrary.wiley.com/doi/10.1034/j.1398-9995.2002.23623.x/abstract | - |
dc.subject.keyword | Der f 2 | - |
dc.subject.keyword | Dermatophagoides farinae | - |
dc.subject.keyword | localization | - |
dc.contributor.alternativeName | Yong, Tai Soon | - |
dc.contributor.affiliatedAuthor | Yong, Tai Soon | - |
dc.contributor.affiliatedAuthor | Jeong, Kyoung Yong | - |
dc.rights.accessRights | not free | - |
dc.citation.volume | 57 | - |
dc.citation.number | 8 | - |
dc.citation.startPage | 729 | - |
dc.citation.endPage | 731 | - |
dc.identifier.bibliographicCitation | ALLERGY, Vol.57(8) : 729-731, 2002 | - |
dc.identifier.rimsid | 38324 | - |
dc.type.rims | ART | - |
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