We have infrequently experienced several cases of secondary achalasia caused by malignancy. Gastric carcinoma is the most common cause of secondary achalasia but other types of malignancy are rarely reported as a cause. Recently, we experienced a case of secondary achalasia and pyloric stenosis in a 62- year-old woman. She had a peripheral cholangiocarcinoma in the left lobe of the liver, which caused secondary achalasia by the direct invasion into the gastroesophageal junction. After 2 months, this malignancy caused pyloric stenosis by direct invasion of the gastric pylorus