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CAPD 환자에서 도관 균락화와 합병된 Penicillium marniffei 복막염 1예

Other Titles
 A Case of Penicillium merneffei CAPD Peritonitis 
 강신욱  ;  한대석  ;  이호영  ;  한상훈  ;  최훈영  ;  이상철  ;  구영석  ;  장경희  ;  김준명  ;  용동은  ;  이경원  ;  신종희  ;  최규현  ;  김준영 
 Korean Journal of Nephrology, Vol.21(4) : 680-685, 2002 
Journal Title
 Korean Journal of Nephrology (대한신장학회지) 
Issue Date
penicillium marneffei ; continuous ambulatory peritoneal dialysis-as-sociated peritonitis
P. marneffei is a fungus that causes life-threatening disseminated infection in a geographically distinct areas of the world. Following the first case of human infection in 1959, the incidence of this infection has risen markedly during the past 5 years. However, even in the midst of such rapid increase, the infection has always occurred only in a limited geographic distributions or in persons who have visited this limited geographic areas. These areas include Myanmar, Hong Kong, Indonesia, Laos, Malaysia, Singapore, Taiwan, Thailand, Vietnam, and the Guangxi province of southern China. P. marneffei infection occurs mostly in immunocompromised patients, particularly AIDS patients. P. marneffei infection commonly presents with skin and subcutanous tissue infection, fungemia, diarrhea, bone marrow infection, and generalized lymphadenopathy with hepatosplenomegaly. We report the case of continuous ambulatory peritoneal dialysis-associated peritonitis caused by P. marneffei. The case occurred in Korea, a non-endemic area of P. marneffei, in a non-AIDS patient who has not been exposed to any of the endemic areas. This warrants further consideration in determining the yet unknown transmission route of this fungal organism. P. marneffei was diagnosed without delay by 18sRNA PCR and sequencing, and was later confirmed by culture. PCR and sequencing may contribute to the early diagnosis of the P. marneffei infection, which is important given this infection`s ability to progress to a systemic infection with high mortality rate when diagnosis and management are delayed.
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1. College of Medicine (의과대학) > Dept. of Internal Medicine (내과학교실) > 1. Journal Papers
1. College of Medicine (의과대학) > Dept. of Laboratory Medicine (진단검사의학교실) > 1. Journal Papers
Yonsei Authors
Kim, June Myung(김준명)
Yong, Dong Eun(용동은) ORCID logo https://orcid.org/0000-0002-1225-8477
Lee, Kyungwon(이경원) ORCID logo https://orcid.org/0000-0003-3788-2134
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