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Synthesis and antiviral activity of novel d- and l-2′-azido-2′,3′-dideoxyribofuranosyl-4′-thiopyrimidines and purines

DC Field Value Language
dc.contributor.author서활-
dc.date.accessioned2016-02-19T11:23:40Z-
dc.date.available2016-02-19T11:23:40Z-
dc.date.issued2001-
dc.identifier.issn0960-894X-
dc.identifier.urihttps://ir.ymlib.yonsei.ac.kr/handle/22282913/143047-
dc.description.abstractNovel D- and L-2'-azido-2',3'-dideoxyribofuranosyl-4'-thiopyrimidines and purines have been synthesized starting from L-xylose and D-xylose, respectively. Among synthesized compounds tested against several viruses such as HIV-1, HSV-1, HSV-2, and HCMV, D-beta-N6-methyladenine (ent-22a) and D-alpha-N6-methyladenine (ent-22b) analogues were found to exhibit significant anti-HCMV activity.-
dc.description.statementOfResponsibilityopen-
dc.format.extent599~603-
dc.relation.isPartOfBIOORGANIC & MEDICINAL CHEMISTRY LETTERS-
dc.rightsCC BY-NC-ND 2.0 KR-
dc.rights.urihttps://creativecommons.org/licenses/by-nc-nd/2.0/kr/-
dc.subject.MESHAntiviral Agents/chemical synthesis*-
dc.subject.MESHAntiviral Agents/pharmacology-
dc.subject.MESHThionucleosides/chemical synthesis*-
dc.subject.MESHThionucleosides/pharmacology-
dc.titleSynthesis and antiviral activity of novel d- and l-2′-azido-2′,3′-dideoxyribofuranosyl-4′-thiopyrimidines and purines-
dc.typeArticle-
dc.contributor.collegeCollege of Medicine (의과대학)-
dc.contributor.departmentDept. of Medical Engineering (의학공학)-
dc.contributor.googleauthorHea Ok Kim-
dc.contributor.googleauthorYun Ha Kim-
dc.contributor.googleauthorHwal Suh-
dc.contributor.googleauthorLak Shin Jeong-
dc.identifier.doi10.1016/S0960-894X(01)00006-3-
dc.admin.authorfalse-
dc.admin.mappingfalse-
dc.contributor.localIdA01924-
dc.relation.journalcodeJ00326-
dc.identifier.eissn1464-3405-
dc.identifier.pmid11229780-
dc.identifier.urlhttp://www.sciencedirect.com/science/article/pii/S0960894X01000063?np=y-
dc.contributor.alternativeNameSuh, Hwal-
dc.contributor.affiliatedAuthorSuh, Hwal-
dc.rights.accessRightsnot free-
dc.citation.volume11-
dc.citation.number4-
dc.citation.startPage599-
dc.citation.endPage603-
dc.identifier.bibliographicCitationBIOORGANIC & MEDICINAL CHEMISTRY LETTERS, Vol.11(4) : 599-603, 2001-
dc.identifier.rimsid38976-
dc.type.rimsART-
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Medical Engineering (의학공학교실) > 1. Journal Papers
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