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궤양성 대장염의 임상경과 : 진단 첫해의 임상경과에 영향을 미치는 인자 및 5년간 임상경과의 변화 양상

Other Titles
 Clinical Course in Ulcerative Colitis : Analysis of the Factors Affecting the Clinical Courses during the First Year, and the Changes of the Clinical Courses during 5Years 
 최창환  ;  정혜원  ;  이재훈  ;  박정엽  ;  이현웅  ;  박영수  ;  김태일  ;  김원호 
 Korean Journal of Gastroenterology, Vol.38(3) : 169-176, 2001 
Journal Title
 Korean Journal of Gastroenterology (대한소화기학회지) 
Issue Date
Ulcerative colitis ; clinical course ; annual disease burden index
Background/Aims: Previous reports on ulcerative colitis in Korea were mostly about clinical features at the time of diagnosis. In this study, we analyzed not only clinical features of Korean patients with ulcerative colitis at the time of diagnosis, but also clinical courses during 5 years after diagnosis. Methods: The yearly sum of monthly symptom scores (annual disease burden index, ADBI), annual symptomatic period, and clinical severity were evaluated during 5 years after diagnosis, and factors affecting the clinical courses during first year were also analyzed. Results: The averages of ADBI, symptomatic period, and the proportion of patients in remission during the first follow-up year were 5.8 ±4.4, 4.0 ±3.1 months, and 22. 1%, Those were 3.7 ±4.1, 3.0 ±3.4 months, and 32.4 %, during the fifth year. The average of ADBI during the second year was significantly higher in patients with high ADBI (>4) during the first year compared with that in patients with low ADBI (6.3 ±5.5 vs. 2.6 ±3.8, p<0.01).Conclusions: From these results, we can conclude that the clinical course of ulcerative colitis, assessed by ADBI and symptomatic period, tends to improve with time and the preceding clinical course is significantly correlated to subsequent course.
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1. College of Medicine (의과대학) > Dept. of Internal Medicine (내과학교실) > 1. Journal Papers
Yonsei Authors
Kim, Won Ho(김원호) ORCID logo https://orcid.org/0000-0002-5682-9972
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