Cited 20 times in
Comparisons of Intraocular-Pressure- Lowering Efficacy and Side Effects of 2% Dorzolamide and 1% Brinzolamide
DC Field | Value | Language |
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dc.contributor.author | 성공제 | - |
dc.date.accessioned | 2016-02-19T11:17:23Z | - |
dc.date.available | 2016-02-19T11:17:23Z | - |
dc.date.issued | 2001 | - |
dc.identifier.issn | 0030-3755 | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/142816 | - |
dc.description.abstract | Forty-one healthy volunteers were recruited for a study to compare the intraocular pressure (IOP)-lowering efficacy and side effects of 2% dorzolamide and 1% brinzolamide. In a randomized double-blind design, one eye received one drop of 2% dorzolamide and the other eye received one drop of 1% brinzolamide. The IOP and side effects were evaluated by Goldmann applanation tonometry and slit lamp biomicroscopy before administration, and 3, 7 and 14 days after the initial administration of eyedrops. The IOP decreased significantly from baseline for both drugs (p < 0.05). However, there were no statistically significant differences between 2% dorzolamide and 1% brinzolamide either before or after eyedrop administration (p > 0.05). The most frequent side effect was ocular pain in the case of 2% dorzolamide and blurred vision in 1% brinzolamide. The results suggested that 2% dorzolamide and 1% brinzolamide have similar IOP-lowering efficacies with different side effects | - |
dc.description.statementOfResponsibility | open | - |
dc.format.extent | 188~191 | - |
dc.relation.isPartOf | OPHTHALMOLOGICA | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.rights.uri | https://creativecommons.org/licenses/by-nc-nd/2.0/kr/ | - |
dc.subject.MESH | Adult | - |
dc.subject.MESH | Carbonic Anhydrase Inhibitors/adverse effects | - |
dc.subject.MESH | Carbonic Anhydrase Inhibitors/pharmacology* | - |
dc.subject.MESH | Double-Blind Method | - |
dc.subject.MESH | Female | - |
dc.subject.MESH | Humans | - |
dc.subject.MESH | Intraocular Pressure/drug effects* | - |
dc.subject.MESH | Male | - |
dc.subject.MESH | Ophthalmic Solutions | - |
dc.subject.MESH | Safety | - |
dc.subject.MESH | Sulfonamides/adverse effects | - |
dc.subject.MESH | Sulfonamides/pharmacology* | - |
dc.subject.MESH | Thiazines/adverse effects | - |
dc.subject.MESH | Thiazines/pharmacology* | - |
dc.subject.MESH | Thiophenes/adverse effects | - |
dc.subject.MESH | Thiophenes/pharmacology* | - |
dc.subject.MESH | Tonometry, Ocular | - |
dc.title | Comparisons of Intraocular-Pressure- Lowering Efficacy and Side Effects of 2% Dorzolamide and 1% Brinzolamide | - |
dc.type | Article | - |
dc.contributor.college | College of Medicine (의과대학) | - |
dc.contributor.department | Dept. of Ophthalmology (안과학) | - |
dc.contributor.googleauthor | Seong G.J. | - |
dc.contributor.googleauthor | Lee S.C. | - |
dc.contributor.googleauthor | Lee J.H. | - |
dc.contributor.googleauthor | Chu Y.K. | - |
dc.contributor.googleauthor | Hong Y.J. | - |
dc.identifier.doi | 10.1159/000050856 | - |
dc.admin.author | false | - |
dc.admin.mapping | false | - |
dc.contributor.localId | A01946 | - |
dc.relation.journalcode | J02431 | - |
dc.identifier.eissn | 1423-0267 | - |
dc.identifier.pmid | 11340389 | - |
dc.identifier.url | http://www.karger.com/Article/FullText/50856 | - |
dc.subject.keyword | Dorzolamide | - |
dc.subject.keyword | Brinzolamide | - |
dc.subject.keyword | Intraocular pressure | - |
dc.subject.keyword | Side effects | - |
dc.contributor.alternativeName | Seong, Gong Je | - |
dc.contributor.affiliatedAuthor | Seong, Gong Je | - |
dc.rights.accessRights | not free | - |
dc.citation.volume | 215 | - |
dc.citation.number | 3 | - |
dc.citation.startPage | 188 | - |
dc.citation.endPage | 191 | - |
dc.identifier.bibliographicCitation | OPHTHALMOLOGICA, Vol.215(3) : 188-191, 2001 | - |
dc.identifier.rimsid | 29874 | - |
dc.type.rims | ART | - |
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