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Comparisons of Intraocular-Pressure- Lowering Efficacy and Side Effects of 2% Dorzolamide and 1% Brinzolamide

DC FieldValueLanguage
dc.contributor.author성공제-
dc.date.accessioned2016-02-19T11:17:23Z-
dc.date.available2016-02-19T11:17:23Z-
dc.date.issued2001-
dc.identifier.issn0030-3755-
dc.identifier.urihttps://ir.ymlib.yonsei.ac.kr/handle/22282913/142816-
dc.description.abstractForty-one healthy volunteers were recruited for a study to compare the intraocular pressure (IOP)-lowering efficacy and side effects of 2% dorzolamide and 1% brinzolamide. In a randomized double-blind design, one eye received one drop of 2% dorzolamide and the other eye received one drop of 1% brinzolamide. The IOP and side effects were evaluated by Goldmann applanation tonometry and slit lamp biomicroscopy before administration, and 3, 7 and 14 days after the initial administration of eyedrops. The IOP decreased significantly from baseline for both drugs (p < 0.05). However, there were no statistically significant differences between 2% dorzolamide and 1% brinzolamide either before or after eyedrop administration (p > 0.05). The most frequent side effect was ocular pain in the case of 2% dorzolamide and blurred vision in 1% brinzolamide. The results suggested that 2% dorzolamide and 1% brinzolamide have similar IOP-lowering efficacies with different side effects-
dc.description.statementOfResponsibilityopen-
dc.format.extent188~191-
dc.relation.isPartOfOPHTHALMOLOGICA-
dc.rightsCC BY-NC-ND 2.0 KR-
dc.rights.urihttps://creativecommons.org/licenses/by-nc-nd/2.0/kr/-
dc.subject.MESHAdult-
dc.subject.MESHCarbonic Anhydrase Inhibitors/adverse effects-
dc.subject.MESHCarbonic Anhydrase Inhibitors/pharmacology*-
dc.subject.MESHDouble-Blind Method-
dc.subject.MESHFemale-
dc.subject.MESHHumans-
dc.subject.MESHIntraocular Pressure/drug effects*-
dc.subject.MESHMale-
dc.subject.MESHOphthalmic Solutions-
dc.subject.MESHSafety-
dc.subject.MESHSulfonamides/adverse effects-
dc.subject.MESHSulfonamides/pharmacology*-
dc.subject.MESHThiazines/adverse effects-
dc.subject.MESHThiazines/pharmacology*-
dc.subject.MESHThiophenes/adverse effects-
dc.subject.MESHThiophenes/pharmacology*-
dc.subject.MESHTonometry, Ocular-
dc.titleComparisons of Intraocular-Pressure- Lowering Efficacy and Side Effects of 2% Dorzolamide and 1% Brinzolamide-
dc.typeArticle-
dc.contributor.collegeCollege of Medicine (의과대학)-
dc.contributor.departmentDept. of Ophthalmology (안과학)-
dc.contributor.googleauthorSeong G.J.-
dc.contributor.googleauthorLee S.C.-
dc.contributor.googleauthorLee J.H.-
dc.contributor.googleauthorChu Y.K.-
dc.contributor.googleauthorHong Y.J.-
dc.identifier.doi10.1159/000050856-
dc.admin.authorfalse-
dc.admin.mappingfalse-
dc.contributor.localIdA01946-
dc.relation.journalcodeJ02431-
dc.identifier.eissn1423-0267-
dc.identifier.pmid11340389-
dc.identifier.urlhttp://www.karger.com/Article/FullText/50856-
dc.subject.keywordDorzolamide-
dc.subject.keywordBrinzolamide-
dc.subject.keywordIntraocular pressure-
dc.subject.keywordSide effects-
dc.contributor.alternativeNameSeong, Gong Je-
dc.contributor.affiliatedAuthorSeong, Gong Je-
dc.rights.accessRightsnot free-
dc.citation.volume215-
dc.citation.number3-
dc.citation.startPage188-
dc.citation.endPage191-
dc.identifier.bibliographicCitationOPHTHALMOLOGICA, Vol.215(3) : 188-191, 2001-
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Ophthalmology (안과학교실) > 1. Journal Papers

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