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인슐린 저항성과 관상동맥 협착증의 상관관계

Other Titles
 Insulin Sensitivity is Associated with the Presence and Extent of Coronary Artery Disease 
 권기환  ;  최동훈  ;  구본권  ;  고영국  ;  변영섭  ;  오성진  ;  민필기 
 Korean Circulation Journal (순환기), Vol.32(7) : 566-572, 2002 
Journal Title
 Korean Circulation Journal  (순환기) 
Issue Date
Background and Objectives : Insulin resistance has been suggested to be an important risk factor in the development of arteriosclerosis. The correlation between insulin sensitivity and the degree of coronary atherosclerosis in patients with angina pectoris was investigated. Subjects and Methods : The study population consisted of 74 subjects with angina (54 men, 20 women), aged from 31 to 73 years. Coronary angiograms were evaluated by 3 semiquantitative scoring systems (vessel score, stenosis score and extent score) to estimate the extent of focal and diffuse coronary artery disease (CAD). Insulin sensitive insulin tolerance test. Results : There were significant correlations between , (PTT) was determined co an IC,TT and all 3 sres. Multivariate analysis revealed significant and independent correlations between all 3 coronary scores and Km, even in patients without diabetes mellitus. Both HDL cholesterol level and KnT were significantly lower in patients with CAD than in those without. Conclusion : Decreased insulin sensitivity was significantly associated with the presence and extent of CAD. These results suggest the potential benefits of insulin-sensitizing treatment strategies for patients with decreased insulin sensitivity.
Appears in Collections:
1. Journal Papers (연구논문) > 1. College of Medicine (의과대학) > Dept. of Internal Medicine (내과학교실)
Yonsei Authors
고영국(Ko, Young Guk)
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