근육병환자와 정상인의 정량적 근전도를 이용한 간섭양상(interference pattern)의 비교

Abstract

Objectives: The aim of this study was to compare with interference pattern of normal and myopathy group. Methods: Sixteen control subjects and nine patients were included. Patients were diagnosed as myopathy by physical examination, history taking, muscle biopsy, laboratory studies including muscle enzyme and polymerase chain reaction for progressive muscular dystrophy. We recorded EMG interference pattern from the biceps muscle, vastus medialis muscle, tibialis anterior muscle. Interference pattern was measured at each electrode position while the subject contracted muscle at different levels of maximal force. The number of turns, mean amplitude, activity, envelope, number of small segments (NSS) were measured from interference pattern recorded at each force level at each site and calculated turns/amplitude ration, envelope/activity ratio, NSS/activity ration. Results: The results of this study revealed stastically significant difference in turns/amplitude ratio, envelope/activity ration, NSS/activity ration between 2 groups. Increased turns/amplitude ratio, decreased envelope/activity ration, incoreased NSS/activity ratio were shown in myopathy group(p<0.01). Conclusion: Automatic interference pattern analysis may contribute to diagnose myopathy in incooperable patients such as young children.