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Non-Hodgkin's Lymphoma & Primary Biliary Cirrhosis with Sjögren's Syndrome

Authors
 Jee Sook Hahn  ;  Chul Kim  ;  Yoo Hong Min  ;  Yun Woong Ko  ;  Chang Ok Suh  ;  Young Yeon Park 
Citation
 YONSEI MEDICAL JOURNAL, Vol.42(2) : 258-263, 2001 
Journal Title
 YONSEI MEDICAL JOURNAL 
ISSN
 0513-5796 
Issue Date
2001
MeSH
Eyelid Neoplasms/etiology* ; Eyelid Neoplasms/pathology ; Female ; Humans ; Liver Cirrhosis, Biliary/complications* ; Liver Cirrhosis, Biliary/pathology ; Lymphoma, B-Cell, Marginal Zone/etiology* ; Lymphoma, B-Cell, Marginal Zone/pathology ; Middle Aged ; Sjogren's Syndrome/complications* ; Sjogren's Syndrome/pathology
Keywords
Sjögren's syndrome ; non-Hodgkin's lymphoma ; PBC ; eyelid
Abstract
Sjögren's syndrome (SS) is an autoimmune disease characterized by a lymphocytic infiltration of the salivary and lacrimal glands leading to a progressive destruction of these glands due to the production of autoantibodies. This disorder is either isolated (primary SS) or associated with other systemic diseases (secondary SS). The occurrence of B-cell non-Hodgkin's lymphoma (NHL) represents the major complication in the evolution of SS patients. The risk of developing NHL, which is equivalent for both primary and secondary SS, was estimated to be 44 times greater than that observed in a comparable normal population. NHLs in SS patients occur preferentially in the salivary glands and in other mucosa-associated lymphoid tissues (MALT). However, it can also occur in the lymph nodes or bone marrow. We documented a case of low-grade B-cell lymphoma of MALT in the right eyelid and primary biliary cirrhosis (PBC) of a patient with SS. To the best of our knowledge, this is the first case reported in Korea.
Files in This Item:
T200101958.pdf Download
DOI
10.3349/ymj.2001.42.2.258
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Pathology (병리학교실) > 1. Journal Papers
1. College of Medicine (의과대학) > Dept. of Internal Medicine (내과학교실) > 1. Journal Papers
Yonsei Authors
Min, Yoo Hong(민유홍) ORCID logo https://orcid.org/0000-0001-8542-9583
Park, Young Nyun(박영년) ORCID logo https://orcid.org/0000-0003-0357-7967
URI
https://ir.ymlib.yonsei.ac.kr/handle/22282913/142289
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