Cited 0 times in
Efficacy of Pre - and Postoperative Chemotherapy in Patients with Osteosarcoma of the Extremities
DC Field | Value | Language |
---|---|---|
dc.contributor.author | 신규호 | - |
dc.contributor.author | 신현준 | - |
dc.contributor.author | 양우익 | - |
dc.contributor.author | 정현철 | - |
dc.contributor.author | 정희철 | - |
dc.contributor.author | 한수봉 | - |
dc.contributor.author | 노재경 | - |
dc.contributor.author | 라선영 | - |
dc.contributor.author | 민진식 | - |
dc.contributor.author | 손주혁 | - |
dc.contributor.author | 구영석 | - |
dc.date.accessioned | 2016-02-19T11:02:53Z | - |
dc.date.available | 2016-02-19T11:02:53Z | - |
dc.date.issued | 2001 | - |
dc.identifier.issn | 1598-2998 | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/142278 | - |
dc.description.abstract | PURPOSE: We evaluated the treatment efficacy including survival and recurrence, and factors associated with recurrence in osteosarcoma patients treated with preoperative chemotherapy, surgery, and adjuvant chemotherapy.0aMATERIALS AND METHODS: Forty nine patients with osteosarcoma were treated with preoperative chemotherapy with intra-arterial cisplatin and adriamycin infusion for 3 cycles, followed by surgery. According to the pathologic response, if tumor was necrotized more than 90%, the same adjuvant chemotherapy was reintroduced for 3 cycles, and if the response was not enough, then the salvage regimen was introduced. Plain chest film and chest CT scan were taken monthly and every 3 months, respectively. When tumor recurred, the metastasectomy was performed whenever possible. 0aRESULTS: Forty three patients were evaluable with amedian follow up of 53 months. Five-year disease-free and overallsurvival rate was 47.0% and 66.9%, respectively. The recurrence was observed in 22 patients (51.2%) with median time of 12.5 months. Baseline alkaline phosphatase (ALP) was the only significant factor for recurrence (pomths vs 5~12 months).0aCONCLUSION: These results indicates that pre- and postoperative chemotherapy with intra-arterial cisplatin and adriamycin infusion showed comparable treatment efficacy and acceptable toxicities. | - |
dc.description.statementOfResponsibility | open | - |
dc.format.extent | 520~526 | - |
dc.relation.isPartOf | CANCER RESEARCH AND TREATMENT | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.rights.uri | https://creativecommons.org/licenses/by-nc-nd/2.0/kr/ | - |
dc.title | Efficacy of Pre - and Postoperative Chemotherapy in Patients with Osteosarcoma of the Extremities | - |
dc.type | Article | - |
dc.contributor.college | College of Medicine (의과대학) | - |
dc.contributor.department | Dept. of Pathology (병리학) | - |
dc.contributor.googleauthor | Joo Hyuk Sohn | - |
dc.contributor.googleauthor | Sun Young Rha | - |
dc.contributor.googleauthor | Hei Cheul Jeung | - |
dc.contributor.googleauthor | Hyun Joon Shin | - |
dc.contributor.googleauthor | Young Suck Goo | - |
dc.contributor.googleauthor | Hyun Cheol Chung | - |
dc.contributor.googleauthor | Woo Ick Yang | - |
dc.contributor.googleauthor | Soo Bong Hahn | - |
dc.contributor.googleauthor | Kyu Ho Shin | - |
dc.contributor.googleauthor | Jin Sik Min | - |
dc.contributor.googleauthor | Byung Soo Kim | - |
dc.contributor.googleauthor | Jae Kyung Roh | - |
dc.contributor.googleauthor | Woo Ick Jang | - |
dc.identifier.doi | 10.4143/crt.2001.33.6.520 | - |
dc.admin.author | false | - |
dc.admin.mapping | false | - |
dc.contributor.localId | A02086 | - |
dc.contributor.localId | A02179 | - |
dc.contributor.localId | A02300 | - |
dc.contributor.localId | A03773 | - |
dc.contributor.localId | A04293 | - |
dc.contributor.localId | A01290 | - |
dc.contributor.localId | A01411 | - |
dc.contributor.localId | A01995 | - |
dc.contributor.localId | A00197 | - |
dc.contributor.localId | A01316 | - |
dc.contributor.localId | A03794 | - |
dc.relation.journalcode | J00453 | - |
dc.identifier.eissn | 2005-9256 | - |
dc.identifier.pmid | 26680832 | - |
dc.subject.keyword | Metastasectomy | - |
dc.subject.keyword | Neoadjuvant chemotherapy | - |
dc.subject.keyword | Osteosarcoma | - |
dc.subject.keyword | Recurrence | - |
dc.contributor.alternativeName | Shin, Kyoo Ho | - |
dc.contributor.alternativeName | Shin, Hyun Joon | - |
dc.contributor.alternativeName | Yang, Woo Ick | - |
dc.contributor.alternativeName | Chung, Hyun Cheol | - |
dc.contributor.alternativeName | Jeung, Hei Cheul | - |
dc.contributor.alternativeName | Hahn, Soo Bong | - |
dc.contributor.alternativeName | Roh, Jae Kyung | - |
dc.contributor.alternativeName | Rha, Sun Young | - |
dc.contributor.alternativeName | Min, Jin Sik | - |
dc.contributor.alternativeName | Sohn, Joo Hyuk | - |
dc.contributor.alternativeName | Goo, Young Suck | - |
dc.contributor.affiliatedAuthor | Shin, Kyoo Ho | - |
dc.contributor.affiliatedAuthor | Shin, Hyun Joon | - |
dc.contributor.affiliatedAuthor | Yang, Woo Ick | - |
dc.contributor.affiliatedAuthor | Chung, Hyun Cheol | - |
dc.contributor.affiliatedAuthor | Hahn, Soo Bong | - |
dc.contributor.affiliatedAuthor | Roh, Jae Kyung | - |
dc.contributor.affiliatedAuthor | Min, Jin Sik | - |
dc.contributor.affiliatedAuthor | Sohn, Joo Hyuk | - |
dc.contributor.affiliatedAuthor | Goo, Young Suck | - |
dc.contributor.affiliatedAuthor | Rha, Sun Young | - |
dc.contributor.affiliatedAuthor | Jeung, Hei Cheul | - |
dc.rights.accessRights | free | - |
dc.citation.volume | 33 | - |
dc.citation.number | 6 | - |
dc.citation.startPage | 520 | - |
dc.citation.endPage | 526 | - |
dc.identifier.bibliographicCitation | CANCER RESEARCH AND TREATMENT, Vol.33(6) : 520-526, 2001 | - |
dc.identifier.rimsid | 31742 | - |
dc.type.rims | ART | - |
Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.