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뇌동정맥기형에 대한 감마나이프 방사선수술시 치료성적에 영향을 주는 인자들

Other Titles
 Factors related to the success of Gamma Knife radiosurgery for arteriovenous malformations 
 장종희  ;  박용구  ;  최재영  ;  장진우  ;  정상섭 
 Journal of Korean Neurosurgical Society (대한신경외과학회지), Vol.30(12) : 1406-1416, 2001 
Journal Title
Journal of Korean Neurosurgical Society(대한신경외과학회지)
Issue Date
Gamma Knife ; Radiosurgery ; Arteriovenous malformation ; Complete occlusion ; Embolization
Objective:The goal of this study was to evaluate the effect of Gamma Knife radiosurgery(GKS) on cerebral arteriovenous malformation(AVM) and the factors associated with complete occlusion.

Patients and Methods:A total of 369 radiosurgical procedures for 336 patients with cerebral AVMs were performed between December 1988 and June 2001. Three hundreds and twenty-four cases of 293 patients who were treated with GKS procedures from May 1992 to December 2000 were analyzed. Various clinical and radiologic parameters were evaluated.

Results:The total obliteration rate for the cases with satisfactory radiological follow-up(more than 2 years) after GKS was 79.3%. In multivariate analysis, maximal diameter, angiographic form of AVM nidus, and number of draining veins significantly influenced the result of radiosurgery. In addition, marginal radiation dose, Spetzler-Martin grade, and flow pattern of AVM nidi also partly influenced the radiosurgical outcome.

Conclusion:GKS on cerebral AVM is considered as an effective treatment modality. The risk of hemorrhage seems to decrease within the latency interval between GKS and complete occlusion of nidus. Along with the size, topography, or radiosurgical parameters of AVMs, it is necessary to consider the angioarchitectural and hemodynamic aspects to select proper candidates for radiosurgery.
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1. College of Medicine (의과대학) > Dept. of Neurosurgery (신경외과학교실) > 1. Journal Papers
Yonsei Authors
Park, Yong Gou(박용구)
Chang, Jong Hee(장종희) ORCID logo https://orcid.org/0000-0003-1509-9800
Chang, Jin Woo(장진우) ORCID logo https://orcid.org/0000-0002-2717-0101
Chung, Sang Sup(정상섭)
Choi, Jae Young(최재영)
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