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돼지 관상동맥 스텐트 재협착 모델에서 Core® Stent와 Palmaz-Schatz® Stent의 비교

Other Titles
 Comparison of Core® Stent and Palmaz-Schatz® Stent in a Porcine Stent Restenosis Model 
 최동훈  ;  최승혁  ;  조덕규  ;  경희두  ;  조정래  ;  김중선  ;  오성진  ;  권승현  ;  장양수  ;  조승연 
 KOREAN CIRCULATION JOURNAL, Vol.31(7) : 655-661, 2001 
Journal Title
Issue Date
Porcine model ; Stents ; Restenosis
Background and Objectives: The purpose of this study is to compare new Core® stent and Palmaz-Schatz® (PS)stent in a porcine coronary stent restenosis model.
Methods: Twelve pigs underwent balloon injury and followed by implantation of oversized, tubular types of Core® and PS® stents (stent/artery ratio 1.2:1) in twenty-four coronary arteries. Quantitative analyses of initial and follow-up coronary angiograms at 4 weeks after stenting were performed. By morphometric analysis, the extents of injury and neointimal area were compared between two stented groups. The stent flexibility and longitudinal staightening effect
were compared between two groups by the bending test and measurement of the angle changes.
Results: 1) Reference vessel diameter, stented artery diameter, and diameter stenosis were not different between two groups. 2) The neointimal area was significantly smaller in the Core® stent group than in the PS® stent group (1.81±0.67㎟ vs 2.93±0.94㎟, p=0.006). 3) Core® stent had more flexible property than PS® stent. 4) The angle changes after stent implantation were not different between two groups(13.2±9.0, 14.4±11.1, p=0.88).
Conclusion: Core® stent is effective in the inhibition of neointimal formation in a porcine coronary stent restenosis model. And this results may be due to more improved flexibility of the Core® stent and further clinical trials may be needed.
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1. College of Medicine (의과대학) > Dept. of Internal Medicine (내과학교실) > 1. Journal Papers
Yonsei Authors
Jang, Yang Soo(장양수) ORCID logo https://orcid.org/0000-0002-2169-3112
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