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Moderate dietary fat consumption as a risk factor for ischemic heart disease in a population with a low fat intake: a case-control study in Korean men

Authors
 Il Suh  ;  Kyung Won Oh  ;  Kang Hee Lee  ;  Bruce M Psaty  ;  Chung Mo Nam  ;  Suk Il Kim  ;  Hyung Gon Kang  ;  Seung Yun Cho  ;  Won Heum Shim 
Citation
 AMERICAN JOURNAL OF CLINICAL NUTRITION, Vol.73(4) : 722-727, 2001 
Journal Title
AMERICAN JOURNAL OF CLINICAL NUTRITION
ISSN
 0002-9165 
Issue Date
2001
MeSH
Alcohol Drinking ; Body Mass Index ; Case-Control Studies ; Diabetes Complications ; Diet, Fat-Restricted ; Dietary Fats/administration & dosage* ; Dietary Fats/adverse effects* ; Exercise ; Humans ; Hyperlipidemias/complications ; Hypertension/complications ; Incidence ; Korea ; Male ; Middle Aged ; Myocardial Infarction/epidemiology ; Myocardial Ischemia/epidemiology* ; Myocardial Ischemia/etiology ; Myocardial Ischemia/prevention & control ; Odds Ratio ; Risk Factors ; Smoking ; Stroke/complications ; Surveys and Questionnaires
Keywords
Ischemic heart disease ; dietary fat intake ; Republic of Korea ; men ; case-control study
Abstract
Background: Dietary fat intake is associated with the incidence of ischemic heart disease (IHD) in Western countries. In populations in which both the average dietary fat consumption and the incidence of IHD are lower than in Western countries, the association of dietary fat intake with IHD incidence remains unknown.

Objective: We conducted a case-control study to examine the association of dietary fat with IHD incidence in Korean men.

Design: The case group consisted of 108 patients with electrocardiogram-confirmed myocardial infarction or angiographically confirmed (≥50% stenosis) IHD who were admitted to a university teaching hospital in Seoul, Republic of Korea. The controls were 142 age-matched patients admitted to the departments of ophthalmology and orthopedic surgery at the same hospital. Dietary fat intake was assessed by a nutritionist using a semiquantitative food-frequency questionnaire. Body mass index (BMI), cigarette use, alcohol intake, exercise, and history of disease were determined during an interview and examination.

Results: In a univariate analysis, the mean percentages of energy from total fat, saturated fatty acids, and monounsaturated fatty acids were significantly higher in the cases than in the controls. BMI, smoking, and a history of hypertension were associated with the occurrence of IHD. In multiple logistic analyses, total fat intake was a significant risk factor (odds ratio: 1.08 for 1% of energy intake; 95% CI: 1.02, 1.14) after adjustment for BMI and smoking.

Conclusion: In a population with a relatively low fat intake (19% of energy intake), a moderate increase in total fat intake may be a risk factor for IHD.
Files in This Item:
T200101587.pdf Download
DOI
10.1093/ajcn/73.4.722
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Preventive Medicine (예방의학교실) > 1. Journal Papers
Yonsei Authors
Nam, Chung Mo(남정모) ORCID logo https://orcid.org/0000-0003-0985-0928
Suh, Il(서일) ORCID logo https://orcid.org/0000-0002-9689-7849
URI
https://ir.ymlib.yonsei.ac.kr/handle/22282913/142097
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