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복부수술후 감염 예방에 대한 Levofloxacin(Cravit®)의 안전성과 유효성에 관한 연구

Other Titles
 Clinical Efficacy and Safety of Intravenous levofloxacin in Patients of Abdominal Operation 
 채윤석  ;  최진섭  ;  이종훈  ;  김경식  ;  이우정  ;  김병로 
 Korean Journal of Hepato-Biliary-Pancreatic Surgery, Vol.5(1) : 169-173, 2001 
Journal Title
Korean Journal of Hepato-Biliary-Pancreatic Surgery(한국간담췌외과학회지)
Issue Date
Levofloxacin ; Quinolone antibiotics
Background/Aims: For the investigation of the efficacy and safety of intravenous levofloxacin, The clinical study was carrried out in 30 patients with abdominal operation, especially in hepatobiliary and pancreatic division.
Methods: Randomly chosen patients received intravenous levofloxacin(250㎎ bid) for only 7 days. Clinical and microbiological evaluation were conducted on the day of starting and finishing levofloxacin treatmeat except for the case of combined use of antibiotics.
Results: The most commonly isolated organism was staphylococcus aureus(33%, 3/9). The overall bacteriologic eradication rate was 67%, (6/9) with clinical success rate was 96%(29/30), There were no significant dverse effects to stop the administration of the drug.
Conclusion: These results suggest that intravenous levofloxacin is effective and safe antibiotics in the fields management of abdominal operation especially in hepatobiliary and pancreas surgery.
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Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Surgery (외과학교실) > 1. Journal Papers
Yonsei Authors
Kim, Kyung Sik(김경식) ORCID logo https://orcid.org/0000-0001-9498-284X
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