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1969-1998년의 장염세균 분리추세

Other Titles
 Isolation Trend of Enteropathogenic Bacteria in 1969-1998 
Authors
 신희봉  ;  정석훈  ;  김원호  ;  이경원  ;  장윤섭 
Citation
 Korean Journal of Clinical Microbiology (대한임상미생물학회지), Vol.4(2) : 87-95, 2001 
Journal Title
 Korean Journal of Clinical Microbiology (대한임상미생물학회지) 
ISSN
 1229-0025 
Issue Date
2001
Keywords
Enteropathogenic bacteria ; Salmonella, Shigella ; Campylobacted Antimicrobial susceptibility
Abstract
Background: Diarrheal disease has been one of the most common health problem in Korea with salmonella and Shigella being the major bacterial pathogens. Prevalence of enteric bacterial pathogens may differ significantly depending on the socioeconomic status of a country. Therefore, rapid improvement of living conditions in Korea should have profound effect on the incidence of enteric infection. In some Salmonella infections, proper antimicrobial treatment is important to reduce morbidity and mortality, but rapid change of the susceptibility makes the susceptibility unpredictable. So, there is a need to describe the change of antimicrobial susceptibility of Salmonella. Methods: In this study, stool culture results at Severance Hospital during the years1969-1998 were analyzed to determine the trends of enteric bacterial isolation and the susceptibilith of the isolates. Results: The proportion of S.tyhi was reduced to 1.4% in 1994-1998. The proportion of Shigella was over 50% of all enteric pathogens until 1983, while only 14 strains were isolated during the last 5 years. Campylobacter spp. became the second most prevalent organism with the decrease of shigella isolation. Ampicillin-and cotrimoxazole-susceptible nontyphoidal Salmonella gradually decreased to 76% and 90%, respectively in 1994-1998 and even several extended-spectrum β-lactamase-producing strains were detected. Strains of ampicillin-resistang S.typhi were first detected in 1995. Conclusions: Typhoid fever and shigellosis are rare disease now in urban clinical setting while nontyphoidal Salmonella infection is a prevalent one. Campylobacter is the second most common enteric bacterial pathogen. With the increase of antimicrobial resistance of nontyphoidal Salmonella and appearance of resistant S.typhi, difficulties in the treatment of these infections may be expected in the future.
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Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Internal Medicine (내과학교실) > 1. Journal Papers
1. College of Medicine (의과대학) > Dept. of Laboratory Medicine (진단검사의학교실) > 1. Journal Papers
Yonsei Authors
Kim, Won Ho(김원호) ORCID logo https://orcid.org/0000-0002-5682-9972
Lee, Kyungwon(이경원) ORCID logo https://orcid.org/0000-0003-3788-2134
URI
https://ir.ymlib.yonsei.ac.kr/handle/22282913/142004
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