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Meta-analysis of hypertension as a risk factor of cerebrovascular disorders in Koreans

Authors
 J. K. Park  ;  C. B. Kim  ;  K. S. Kim  ;  M. G. Kang  ;  S. H. Jee 
Citation
 JOURNAL OF KOREAN MEDICAL SCIENCE, Vol.16(1) : 2-8, 2001 
Journal Title
JOURNAL OF KOREAN MEDICAL SCIENCE
ISSN
 1011-8934 
Issue Date
2001
MeSH
Humans ; Hypertension/complications* ; Randomized Controlled Trials as Topic ; Risk Factors ; Stroke/etiology*
Keywords
Cerebrovascular Disorders ; Hypertension ; Meta-Analysis ; Korea
Abstract
This study was conducted to integrate the results of previous studies which evaluated hypertension as a risk factor for cerebrovascular disorders (CVD) in Koreans. We retrieved the Korean literature using a manual search and the English literature using the MEDLINE database concerning the relationship between hypertension and CVD in Koreans from 1980 to 1997. The overall effect size of hypertension as a risk factor of CVD was represented by common odds ratio (OR). Before the integration of each effect size, a heterogeneity test and a sensitivity test was conducted. The materials were nine published epidemiologic studies with a total of 2,271 cases of CVD. The common ORs (95% confidence interval) of overall CVD, hemorrhagic CVD and ischemic CVD associated with hypertension were 4.10 (3.56-4.71), 6.56 (4.92-8.80) and 3.28 (2.77-3.90), respectively. Thus, the common OR of hemorrhagic CVD associated with hypertension was significantly higher than that of overall or ischemic CVD. This suggests that hypertension is an important risk factor for overall CVD and its subtypes in Koreans. Due to the lack of reliable prospective studies, however, longitudinal study is required in this area.
Files in This Item:
T200101152.pdf Download
DOI
10.3346/jkms.2001.16.1.2
Appears in Collections:
4. Graduate School of Public Health (보건대학원) > Graduate School of Public Health (보건대학원) > 1. Journal Papers
Yonsei Authors
Jee, Sun Ha(지선하) ORCID logo https://orcid.org/0000-0001-9519-3068
URI
https://ir.ymlib.yonsei.ac.kr/handle/22282913/141945
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