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CD5와 Cytokeratin 7에 음성이고 Cytokeratin 13에 양성인 흉선 편평상피세포암 1예

Other Titles
 A case of Squamous cell Carcinoma of Thymus with Negative CD5,Cytokeratin 7 and Positive Cytokeratin 13 
Authors
 박무석  ;  정재호  ;  노태웅  ;  손주혁  ;  김영삼  ;  장준  ;  정경영  ;  김주항  ;  김성규  ;  신동환  ;  김세규 
Citation
 Tuberculosis and Respiratory Diseases (결핵 및 호흡기질환), Vol.51(3) : 281-288, 2001 
Journal Title
 Tuberculosis and Respiratory Diseases (결핵 및 호흡기질환) 
ISSN
 3780-0066 
Issue Date
2001
Keywords
Squamous cell carcinoma ; Unknown primary origin ; Mediastinum ; CD5 ; Cytokeratin ; Thymic carcinoma ; Lung cancer
Abstract
Background : The most common anterior mediastinal tumors originate from the thymus. Among them, thymic carcinomas occur as an early local invasion and wide spread metastases. However, when squamous cell carcinoma in the thymus or mediastinum is identified, an occult primary lung cancer must be excluded because the histologic types resemble those found more typically in the lung. CD5 and cytokeratin immunohistochemical staining is useful in evaluating biopsy samples from those tumors. Squamous cell carcinoma of an unknown primary origin in the mediastinum is a rare occurrence and there are only a handful of case reports. Here we describe a case with an anterior mediastinal mass of squamous cell carcinoma with unknown primary origin. A resection of the mediastinal mass without an association with the lung was performed. Immunohistochemical stallings were positive using cytokeratin 13, and negative using CD5 and cytokeratin 7. This was followed by chemotherapy for presumed thymic carcinoma.
Files in This Item:
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Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Thoracic and Cardiovascular Surgery (흉부외과학교실) > 1. Journal Papers
1. College of Medicine (의과대학) > Dept. of Pathology (병리학교실) > 1. Journal Papers
1. College of Medicine (의과대학) > Dept. of Internal Medicine (내과학교실) > 1. Journal Papers
Yonsei Authors
Kim, Sung Kyu(김성규)
Kim, Se Kyu(김세규)
Kim, Young Sam(김영삼) ORCID logo https://orcid.org/0000-0001-9656-8482
Kim, Joo Hang(김주항)
Noh, Tae Woong(노태웅)
Park, Moo Suk(박무석) ORCID logo https://orcid.org/0000-0003-0820-7615
Sohn, Joo Hyuk(손주혁) ORCID logo https://orcid.org/0000-0002-2303-2764
Shin, Dong Hwan(신동환)
Chang, Joon(장준) ORCID logo https://orcid.org/0000-0003-4542-6841
Chung, Kyung Young(정경영)
Chung, Jae Ho(정재호)
URI
https://ir.ymlib.yonsei.ac.kr/handle/22282913/141925
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