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Is Single Administration of Prophylactic Antibiotics Enough after Laparoscopic Appendectomy for Uncomplicated Appendicitis?

 Soon Min Choi  ;  Seung Hwan Lee  ;  Ji Young Jang  ;  Hyung Won Kim  ;  Myung Jae Jung  ;  Jae Gil Lee 
 Journal of Acute Care Surgery, Vol.5(2) : 59-63, 2015 
Journal Title
 Journal of Acute Care Surgery 
Issue Date
Purpose: Research comparing the effectiveness of different doses of antibiotics prior to surgery for preventing infection is sparse. This study examines whether a single dose of preoperative antibiotics suffices to treat uncomplicated appendicitis via laparoscopic appendectomy. Methods: This study retrospectively reviewed the medical records of 149 patients who underwent laparoscopic appendectomy from July 2013 to December 2014 in a single institution. The participants were divided into two groups; group A (n=99) was given a single dose of prophylactic antibiotics before surgery, and group B (n=50) was given both preoperative and postoperative antibiotics. Clinical factors and surgical outcomes were compared between two groups. Results: The mean length of hospital stay for group A (2.5 days) was shorter than for group B (3.2 days) (p<0.001). Average operation time was 58.7 minutes for group A, longer than for group B (52.2 minutes, p=0.027). There was no difference in pathologic results and postoperative complications, such as surgical site infection (SSI) between the two groups. In groups A and B, 4.0% of patients had superficial SSIs. One patient (2.0%) in group B had deep/organ SSI. Conclusion: A single dose of prophylactic antibiotics administration to patients undergoing laparoscopic appendectomy is acceptable as a treatment in uncomplicated appendicitis.
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1. Journal Papers (연구논문) > 1. College of Medicine (의과대학) > Dept. of Surgery (외과학교실)
Yonsei Authors
김형원(Kim, Hyung Won)
이승환(Lee, Seung Hwan) ORCID logo https://orcid.org/0000-0001-7325-8262
이재길(Lee, Jae Gil) ORCID logo https://orcid.org/0000-0002-1148-8035
장지영(Jang, Ji Young)
정명재(Jung, Myung Jae)
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