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Postural vital capacity difference with aging in duchenne muscular dystrophy

DC FieldValueLanguage
dc.contributor.author강성웅-
dc.contributor.author최원아-
dc.date.accessioned2016-02-04T12:00:16Z-
dc.date.available2016-02-04T12:00:16Z-
dc.date.issued2015-
dc.identifier.issn0148-639X-
dc.identifier.urihttps://ir.ymlib.yonsei.ac.kr/handle/22282913/141678-
dc.description.abstractINTRODUCTION: A change in vital capacity (VC) from standing to supine can be an index of diaphragm paralysis if it exceeds 25%. We aimed to verify whether the postural VC difference increases with age and reflects diaphragm weakness in DMD. METHODS: VCs were measured in DMD. Postural VC difference and percentage were calculated from the VC data. Maximal inspiratory pressure (MIP) and MIP percentage were measured as an indirect index of diaphragm weakness. RESULTS: A total of 220 patients and 544 measurements were collected. MIP and MIP percentage decreased significantly with age (P < 0.001 for both). Estimated postural VC difference and percentage also decreased (P < 0.001, P = 0.006, respectively). Age group comparisons showed a significant decrease in younger, but not older subjects. CONCLUSIONS: This study shows that the postural VC difference tended to decrease with age and might not reflect diaphragmatic weakness in DMD; however, this should be interpreted cautiously.-
dc.description.statementOfResponsibilityopen-
dc.format.extent722~727-
dc.relation.isPartOfMUSCLE & NERVE-
dc.rightsCC BY-NC-ND 2.0 KR-
dc.rights.urihttps://creativecommons.org/licenses/by-nc-nd/2.0/kr/-
dc.subject.MESHAdolescent-
dc.subject.MESHAdult-
dc.subject.MESHAging/pathology*-
dc.subject.MESHAging/physiology*-
dc.subject.MESHChild-
dc.subject.MESHFollow-Up Studies-
dc.subject.MESHHumans-
dc.subject.MESHInspiratory Capacity/physiology-
dc.subject.MESHMale-
dc.subject.MESHMuscular Dystrophy, Duchenne/diagnosis*-
dc.subject.MESHMuscular Dystrophy, Duchenne/physiopathology*-
dc.subject.MESHPosture/physiology*-
dc.subject.MESHRespiratory Muscles/pathology-
dc.subject.MESHRespiratory Muscles/physiopathology-
dc.subject.MESHRetrospective Studies-
dc.subject.MESHVital Capacity/physiology*-
dc.subject.MESHYoung Adult-
dc.titlePostural vital capacity difference with aging in duchenne muscular dystrophy-
dc.typeArticle-
dc.contributor.collegeCollege of Medicine (의과대학)-
dc.contributor.departmentDept. of Rehabilitation Medicine (재활의학)-
dc.contributor.googleauthorYu Hui Won-
dc.contributor.googleauthorWon Ah Choi-
dc.contributor.googleauthorDong Hyun Kim-
dc.contributor.googleauthorSeong-Woong Kang-
dc.identifier.doi10.1002/mus.24623-
dc.admin.authorfalse-
dc.admin.mappingfalse-
dc.contributor.localIdA00041-
dc.contributor.localIdA04125-
dc.relation.journalcodeJ02278-
dc.identifier.eissn1097-4598-
dc.identifier.pmid25727906-
dc.identifier.urlhttp://onlinelibrary.wiley.com/doi/10.1002/mus.24623/abstract-
dc.subject.keywordDuchenne muscular dystrophy-
dc.subject.keywordage-
dc.subject.keyworddiaphragm-
dc.subject.keywordmaximal inspiratory pressure-
dc.subject.keywordpostural vital capacity difference-
dc.contributor.alternativeNameKang, Seong Woong-
dc.contributor.alternativeNameChoi, Won Ah-
dc.contributor.affiliatedAuthorKang, Seong Woong-
dc.contributor.affiliatedAuthorChoi, Won Ah-
dc.rights.accessRightsnot free-
dc.citation.volume52-
dc.citation.number5-
dc.citation.startPage722-
dc.citation.endPage727-
dc.identifier.bibliographicCitationMUSCLE & NERVE, Vol.52(5) : 722-727, 2015-
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Rehabilitation Medicine (재활의학교실) > 1. Journal Papers

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