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Value of utilizing both ASPECTS and CT angiography collateral score for outcome prediction in acute ischemic stroke

DC FieldValueLanguage
dc.contributor.author김영대-
dc.contributor.author김은혜-
dc.contributor.author김진권-
dc.contributor.author남효석-
dc.contributor.author송동범-
dc.contributor.author송태진-
dc.contributor.author이기정-
dc.contributor.author이혜선-
dc.contributor.author허지회-
dc.date.accessioned2016-02-04T11:58:32Z-
dc.date.available2016-02-04T11:58:32Z-
dc.date.issued2015-
dc.identifier.issn1747-4930-
dc.identifier.urihttps://ir.ymlib.yonsei.ac.kr/handle/22282913/141614-
dc.description.abstractBACKGROUND: Alberta Stroke Program Early CT Score (ASPECTS) represents the extent of irreversibly damaged tissue; while CT angiography collateral score (CTA-CS) denotes the degree of collaterals. AIMS: We investigated whether there is cumulative value in using both ASPECTS and CTA-CS for outcome prediction and attempted to determine the specific subgroup of patients who could benefit from successful reperfusion using these scores. METHODS: This is a retrospective observational study of stroke patients treated with intra-arterial reperfusion therapy for unilateral arterial occlusion in the anterior circulation. A favorable outcome was defined as modified Rankin Scale ≤ 2 at three-months. Receiver operating characteristic comparison analysis was performed to decide whether outcome predictability increases when ASPECTS and CTA-CS are used together. Classification and regression tree (CART) analysis was done to identify the variables that best predict outcome and define the specific subgroup of patients who could benefit from successful reperfusion. RESULTS: A total of 91 consecutive patients were included. Outcome predictability of ASPECTS with CTA-CS was better than that of ASPECTS (P = 0·088) or that of CTA-CS (P = 0·049). CART analysis revealed that ASPECTS > 5 was the primary determinant of favorable outcome, followed by CTA-CS > 1. Among 19 patients with ASPECTS ≤ 5, none had a favorable outcome. Successful reperfusion was associated significantly with favorable outcome in the 51 patients with ASPECTS > 5 and CTA-CS > 1, but not in the 21 patients with ASPECTS > 5 and CTA-CS ≤ 1. CONCLUSIONS: Outcome predictability improves when using ASPECTS and CTA-CS together.-
dc.description.statementOfResponsibilityopen-
dc.format.extent1018~1023-
dc.relation.isPartOfInternational Journal of Stroke-
dc.rightsCC BY-NC-ND 2.0 KR-
dc.rights.urihttps://creativecommons.org/licenses/by-nc-nd/2.0/kr/-
dc.titleValue of utilizing both ASPECTS and CT angiography collateral score for outcome prediction in acute ischemic stroke-
dc.typeArticle-
dc.contributor.collegeCollege of Medicine (의과대학)-
dc.contributor.departmentDept. of Neurology (신경과학)-
dc.contributor.googleauthorDongbeom Song-
dc.contributor.googleauthorKijeong Lee-
dc.contributor.googleauthorEun Hye Kim-
dc.contributor.googleauthorYoung Dae Kim-
dc.contributor.googleauthorJinkwon Kim-
dc.contributor.googleauthorTae-Jin Song-
dc.contributor.googleauthorHye Sun Lee-
dc.contributor.googleauthorHyo Suk Nam-
dc.contributor.googleauthorJi Hoe Heo-
dc.identifier.doi10.1111/ijs.12505-
dc.admin.authorfalse-
dc.admin.mappingfalse-
dc.contributor.localIdA00702-
dc.contributor.localIdA01012-
dc.contributor.localIdA01273-
dc.contributor.localIdA02017-
dc.contributor.localIdA02073-
dc.contributor.localIdA02696-
dc.contributor.localIdA04369-
dc.contributor.localIdA03312-
dc.contributor.localIdA00828-
dc.relation.journalcodeJ01161-
dc.identifier.urlhttp://onlinelibrary.wiley.com/doi/10.1111/ijs.12505/abstract-
dc.contributor.alternativeNameKim, Young Dae-
dc.contributor.alternativeNameKim, Eun Hye-
dc.contributor.alternativeNameKim, Jin Kwon-
dc.contributor.alternativeNameNam, Hyo Suk-
dc.contributor.alternativeNameSong, Dong Beom-
dc.contributor.alternativeNameSong, Tae Jin-
dc.contributor.alternativeNameLee, Ki Jeong-
dc.contributor.alternativeNameLee, Hye Sun-
dc.contributor.alternativeNameHeo, Ji Hoe-
dc.contributor.affiliatedAuthorKim, Young Dae-
dc.contributor.affiliatedAuthorKim, Jin Kwon-
dc.contributor.affiliatedAuthorNam, Hyo Suk-
dc.contributor.affiliatedAuthorSong, Dong Beom-
dc.contributor.affiliatedAuthorSong, Tae Jin-
dc.contributor.affiliatedAuthorLee, Ki Jeong-
dc.contributor.affiliatedAuthorHeo, Ji Hoe-
dc.contributor.affiliatedAuthorLee, Hye Sun-
dc.contributor.affiliatedAuthorKim, Eun Hye-
dc.rights.accessRightsnot free-
dc.citation.volume10-
dc.citation.number7-
dc.citation.startPage1018-
dc.citation.endPage1023-
dc.identifier.bibliographicCitationInternational Journal of Stroke, Vol.10(7) : 1018-1023, 2015-
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Neurology (신경과학교실) > 1. Journal Papers
1. College of Medicine (의과대학) > Yonsei Biomedical Research Center (연세의생명연구원) > 1. Journal Papers

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