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Topographical variation of macular choroidal thickness with myopia

DC FieldValueLanguage
dc.contributor.author이성철-
dc.contributor.author이승규-
dc.contributor.author이준원-
dc.date.accessioned2016-02-04T11:55:01Z-
dc.date.available2016-02-04T11:55:01Z-
dc.date.issued2015-
dc.identifier.issn1755-375X-
dc.identifier.urihttps://ir.ymlib.yonsei.ac.kr/handle/22282913/141483-
dc.description.abstractPURPOSE: To study the association between topographical variation of choroidal thickness and myopic features in healthy eyes, using spectral domain optical coherence tomography (OCT). METHODS: Choroidal thickness was measured at the foveal centre (CTF) and 1.5 mm superiorly (CTS), inferiorly (CTI), nasally (CTN) and temporally (CTT) from the foveal centre, using enhanced depth imaging OCT. The temporal width of β zone of peripapillary atrophy (βPPA) was measured on infrared fundus images. The ratio of βPPA width to vertical disc diameter (PVDR) was calculated to correct retinal magnification. RESULTS: This study includes 85 eyes from 85 subjects who had a mean age of 53.9 ± 12.9 years, a mean axial length of 23.56 ± 0.82 mm, a mean refractive error of -0.14 ± 1.80 D, a mean βPPA width of 218.6 ± 181.3 μm and a mean PVDR of 0.13 ± 0.11. The CTF was thickest (266.4 ± 81.6), followed by CTS (256.2 ± 82.5 μm), CTT (251.7 ± 68.4 μm), CTI (247.7 ± 90.3 μm) and CTN (211.0 ± 76.5 μm). There were 31 eyes (36.5%) with CTT thicker than CTF. The CTT/CTF negatively correlated with refractive error (p = 0.012) and positively correlated with axial length (p = 0.031), βPPA width (p = 0.003) and PVDR (p = 0.006). CONCLUSIONS: There was a correlation between a thickened choroid, temporal to the foveal centre, with the severity of myopic components in normal eyes. Topographical changes might be induced by stretching of the choroid and sclera towards a temporal direction with eyeball elongation.-
dc.description.statementOfResponsibilityopen-
dc.relation.isPartOfACTA OPHTHALMOLOGICA-
dc.rightsCC BY-NC-ND 2.0 KR-
dc.rights.urihttps://creativecommons.org/licenses/by-nc-nd/2.0/kr/-
dc.subject.MESHAdult-
dc.subject.MESHAged-
dc.subject.MESHAxial Length, Eye/pathology-
dc.subject.MESHChoroid/pathology*-
dc.subject.MESHCross-Sectional Studies-
dc.subject.MESHFemale-
dc.subject.MESHFovea Centralis-
dc.subject.MESHHumans-
dc.subject.MESHMale-
dc.subject.MESHMiddle Aged-
dc.subject.MESHMyopia/classification-
dc.subject.MESHMyopia/physiopathology*-
dc.subject.MESHOrgan Size-
dc.subject.MESHRetrospective Studies-
dc.subject.MESHSeverity of Illness Index-
dc.subject.MESHTomography, Optical Coherence-
dc.subject.MESHVisual Acuity-
dc.subject.MESHYoung Adult-
dc.titleTopographical variation of macular choroidal thickness with myopia-
dc.typeArticle-
dc.contributor.collegeCollege of Medicine (의과대학)-
dc.contributor.departmentDept. of Ophthalmology (안과학)-
dc.contributor.googleauthorKwanghyun Lee-
dc.contributor.googleauthorJunwon Lee-
dc.contributor.googleauthorChristopher S. Lee-
dc.contributor.googleauthorSun Young Park-
dc.contributor.googleauthorSung Chul Lee-
dc.contributor.googleauthorTaekJune Lee-
dc.identifier.doi10.1111/aos.12701-
dc.admin.authorfalse-
dc.admin.mappingfalse-
dc.contributor.localIdA02873-
dc.contributor.localIdA02913-
dc.relation.journalcodeJ00025-
dc.identifier.eissn1755-3768-
dc.identifier.pmid25752626-
dc.identifier.urlhttp://onlinelibrary.wiley.com/doi/10.1111/aos.12701/abstract-
dc.subject.keywordchoroidal thickness-
dc.subject.keywordmyopia-
dc.subject.keywordnormal subjects-
dc.subject.keywordperipapillary atrophy-
dc.contributor.alternativeNameLee, Sung Chul-
dc.contributor.alternativeNameLee, Seung Kyu-
dc.contributor.affiliatedAuthorLee, Sung Chul-
dc.contributor.affiliatedAuthorLee, Seung Kyu-
dc.rights.accessRightsnot free-
dc.citation.volume93-
dc.citation.number6-
dc.citation.startPage469-
dc.citation.endPage474-
dc.identifier.bibliographicCitationACTA OPHTHALMOLOGICA, Vol.93(6) : 469-474, 2015-
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Ophthalmology (안과학교실) > 1. Journal Papers

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