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Effect of a Low Iodine Diet vs. Restricted Iodine Diet on Postsurgical Preparation for Radioiodine Ablation Therapy in Thyroid Carcinoma Patients

 Chi Young Lim  ;  Jung-Yeon Kim  ;  Mi-Jin Yoon  ;  Hang Seok Chang  ;  Cheong Soo Park  ;  Woong Youn Chung 
 YONSEI MEDICAL JOURNAL, Vol.56(4) : 1021-1027, 2015 
Journal Title
Issue Date
Ablation Techniques ; Adult ; Carcinoma/metabolism ; Carcinoma/radiotherapy* ; Carcinoma/surgery ; Diet* ; Female ; Humans ; Iodides/urine ; Iodine/administration & dosage ; Iodine/urine ; Iodine Radioisotopes/metabolism ; Iodine Radioisotopes/therapeutic use* ; Male ; Middle Aged ; Republic of Korea ; Thyroid Neoplasms/metabolism ; Thyroid Neoplasms/radiotherapy* ; Thyroid Neoplasms/surgery ; Thyroidectomy ; Treatment Outcome
Thyroid carcinoma ; iodine diet ; radioiodine ablation therapy
PURPOSE: The radioiodine ablation therapy is required for patients who underwent a total thyroidectomy. Through a comparative review of a low iodine diet (LID) and a restricted iodine diet (RID), the study aims to suggest guidelines that are suitable for the conditions of Korea. MATERIALS AND METHODS: The study was conducted with 101 patients. With 24-hour urine samples from the patients after a 2-week restricted diet and after a 4-week restricted diet, the amount of iodine in the urine was estimated. The consumed radioiodine amounts for 2 hours and 24 hours were calculated. RESULTS: This study was conducted with 47 LID patients and 54 RID patients. The amounts of iodine in urine, the 2-week case and 4-week case for each group showed no significant differences. The amounts of iodine in urine between the two groups were both included in the range of the criteria for radioiodine ablation therapy. Also, 2 hours and 24 hours radioiodine consumption measured after 4-week restrictive diet did not show statistical differences between two groups. CONCLUSION: A 2-week RID can be considered as a type of radioiodine ablation therapy after patients undergo a total thyroidectomy.
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Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Nuclear Medicine (핵의학교실) > 1. Journal Papers
1. College of Medicine (의과대학) > Dept. of Surgery (외과학교실) > 1. Journal Papers
Yonsei Authors
Park, Cheong Soo(박정수)
Yun, Mi Jin(윤미진) ORCID logo https://orcid.org/0000-0002-1712-163X
Chang, Hang Seok(장항석) ORCID logo https://orcid.org/0000-0002-5162-103X
Chung, Woung Youn(정웅윤)
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