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Mutual relationship between anxiety and pain in the intensive care unit and its effect on medications

 Jooyoung Oh  ;  Jeong-Hyun Sohn  ;  Cheung Soo Shin  ;  Se Hee Na  ;  Hyung-Jun Yoon  ;  Jae-Jin Kim  ;  Sunyoung Park  ;  Jin Young Park 
 JOURNAL OF CRITICAL CARE, Vol.30(5) : 1043-1048, 2015 
Journal Title
Issue Date
Adult ; Aged ; Analgesics, Opioid/therapeutic use* ; Anti-Anxiety Agents/therapeutic use* ; Anxiety Disorders/drug therapy* ; Critical Care/methods ; Critical Illness ; Female ; Humans ; Intensive Care Units ; Male ; Middle Aged ; Pain/prevention & control* ; Pain Measurement
Anxiety ; Anxiolytics ; Distress ; Intensive care unit ; Opioid ; Pain
PURPOSE: Little is known about the relationship between anxiety and pain in intensive care unit (ICU) patients despite its importance. The aims of the present study are to examine the correlation between pain and anxiety during ICU care and to investigate its effects on the dose of opioids and anxiolytics administered. METHODS: The study subjects were awake critically ill patients admitted to an ICU over a 2-month period. Trained psychiatrists evaluated the nondelirious, noncomatose patients daily for anxiety and pain using the Numeric Rating Scale for Pain (NRS-Pain), Faces Anxiety Scale (FAS), and Hamilton Anxiety Rating Scale. RESULTS: Daily alterations of anxiety and pain were significantly correlated with one another among 123 patients. Both the FAS and the Hamilton Anxiety Rating Scale were positively correlated with the NRS-Pain (P < .001 for both). The NRS-Pain score (P = .016) and the FAS score (P = .007) both significantly correlated with the dose of anxiolytics. The dose of opioids was unaffected by the severity of pain or anxiety. CONCLUSIONS: Pain and anxiety among critically ill patients in the ICU were closely correlated. Pain and anxiety influenced the dose of anxiolytics administered. Therefore, a precise evaluation and comprehensive approach to the management of pain and anxiety are important for treating ICU patients.
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1. College of Medicine (의과대학) > Dept. of Psychiatry (정신과학교실) > 1. Journal Papers
1. College of Medicine (의과대학) > Dept. of Anesthesiology and Pain Medicine (마취통증의학교실) > 1. Journal Papers
Yonsei Authors
Kim, Jae Jin(김재진) ORCID logo https://orcid.org/0000-0002-1395-4562
Na, Se Hee(라세희) ORCID logo https://orcid.org/0000-0003-4208-0769
Park, Sunyoung(박선영)
Park, Jin Young(박진영) ORCID logo https://orcid.org/0000-0002-5351-9549
Shin, Cheung Soo(신증수) ORCID logo https://orcid.org/0000-0001-7829-8458
Oh, Jooyoung(오주영) ORCID logo https://orcid.org/0000-0001-6721-399X
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