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결절성 경화증 (Tuberous sclerosis) 환자에서 뇌실막밑 거대세포 별아교세포종의 (Subependymal giant cell astrocytoma) 치료

Other Titles
 Management of Subependymal Giant Cell Astrocytomas in Patients with Tuberous Sclerosis 
Authors
 조민수  ;  강훈철  ;  김흥동  ;  이준수  ;  김동석  ;  김정아 
Citation
 Journal of the Korean Child Neurology Society (대한소아신경학회지), Vol.23(1) : 1-6, 2015 
Journal Title
 Journal of the Korean Child Neurology Society  (대한소아신경학회지) 
ISSN
 1226-6884 
Issue Date
2015
Abstract
Purpose: Subependymal giant cell astrocytomas (SEGAs) are a well-known complication of tuberous sclerosis complex (TSC). Treatment experience has been accumulated for several years. The aim of this study was to review our experiences in treatment of SEGAs and prognosis. Method: From March 2007 to March 2014, 161 TSC patients were diagnosed. Of 161 patients, 17 patients met diagnostic criteria of SEGAs. We reviewed clinical data of SEGA patients retrogradely. Results: Among 17 SEGAs patients, five patients underwent surgical treatment. Of five patients who underwent surgery, including two patients who underwent gamma knife surgery before tumorectomy, four patients underwent tumorectomy, and one patient underwent shunt operation. Out of four patients who underwent surgery, two patients with increased intracranial pressure (IICP) symptoms before surgery showed worse neurological outcome than the other two patients without IICP symptoms. Conclusion: Our experiences suggest that early surgical intervention should be considered as one of treatment modalities for asymptomatic SEGA patients.
URI
https://ir.ymlib.yonsei.ac.kr/handle/22282913/141358
Appears in Collections:
1. Journal Papers (연구논문) > 1. College of Medicine (의과대학) > Dept. of Neurosurgery (신경외과학교실)
1. Journal Papers (연구논문) > 1. College of Medicine (의과대학) > Dept. of Pediatrics (소아청소년과학교실)
Yonsei Authors
강훈철(Kang, Hoon Chul) ; 김동석(Kim, Dong Seok) ; 김정아(Kim, Jeong A) ; 김흥동(Kim, Heung Dong) ; 이준수(Lee, Joon Soo)
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