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Development of Thyroid-Associated Ophthalmopathy in Patients Who Underwent Total Thyroidectomy

DC FieldValueLanguage
dc.contributor.author윤진숙-
dc.date.accessioned2016-02-04T11:50:35Z-
dc.date.available2016-02-04T11:50:35Z-
dc.date.issued2015-
dc.identifier.issn0513-5796-
dc.identifier.urihttps://ir.ymlib.yonsei.ac.kr/handle/22282913/141325-
dc.description.abstractPURPOSE: To report clinical characteristics of thyroid-associated ophthalmopathy (TAO) in patients who previously underwent total thyroidectomy for thyroid cancer or a benign mass of the thyroid. MATERIALS AND METHODS: Of the patients who were diagnosed with TAO from March 2008 to March 2012, we performed a retrospective chart review on those who had undergone total thyroidectomy for thyroid cancer or a benign mass of the thyroid before the occurrence of ophthalmopathy. RESULTS: Of the 206 patients diagnosed with TAO, seven (3.4%) met the inclusion criteria. The mean age of the subjects was 47.4 years, and all were female. Six patients were diagnosed with papillary thyroid cancer, and one was diagnosed with a benign mass. The duration between total thyroidectomy and onset of TAO ranged from 3-120 months (median 48 months). Ophthalmic manifestations varied among cases. Except for the patient who was diagnosed with a benign mass, all patients showed hyperthyroid status and were under Synthroid hormone treatment at the time of TAO development. Five of these six patients had positive levels of thyroid-stimulating hormone (TSH) receptor autoantibodies. CONCLUSION: TAO rarely develops after total thyroidectomy, and the mechanism of TAO occurrence is unclear. However, most patients showed abnormalities in thyroid function and TSH receptor autoantibodies.-
dc.description.statementOfResponsibilityopen-
dc.format.extent1389~1394-
dc.relation.isPartOfYONSEI MEDICAL JOURNAL-
dc.rightsCC BY-NC-ND 2.0 KR-
dc.rights.urihttps://creativecommons.org/licenses/by-nc-nd/2.0/kr/-
dc.subject.MESHAdult-
dc.subject.MESHAged-
dc.subject.MESHAutoantibodies/blood-
dc.subject.MESHCarcinoma-
dc.subject.MESHCarcinoma, Papillary/immunology-
dc.subject.MESHCarcinoma, Papillary/surgery-
dc.subject.MESHFemale-
dc.subject.MESHGraves Ophthalmopathy/diagnosis*-
dc.subject.MESHGraves Ophthalmopathy/immunology-
dc.subject.MESHHumans-
dc.subject.MESHMale-
dc.subject.MESHMiddle Aged-
dc.subject.MESHPostoperative Complications/etiology-
dc.subject.MESHPostoperative Complications/immunology-
dc.subject.MESHPostoperative Complications/pathology-
dc.subject.MESHReceptors, Thyrotropin-
dc.subject.MESHRetrospective Studies-
dc.subject.MESHThyroid Neoplasms/complications-
dc.subject.MESHThyroid Neoplasms/surgery*-
dc.subject.MESHThyroidectomy/adverse effects-
dc.subject.MESHThyroidectomy/methods*-
dc.subject.MESHThyrotropin/blood-
dc.subject.MESHTreatment Outcome-
dc.titleDevelopment of Thyroid-Associated Ophthalmopathy in Patients Who Underwent Total Thyroidectomy-
dc.typeArticle-
dc.contributor.collegeCollege of Medicine (의과대학)-
dc.contributor.departmentDept. of Ophthalmology (안과학)-
dc.contributor.googleauthorSun Young Jang-
dc.contributor.googleauthorKa Hyun Lee-
dc.contributor.googleauthorJong Rok Oh-
dc.contributor.googleauthorBo Yeon Kim-
dc.contributor.googleauthorJin Sook Yoon-
dc.identifier.doi10.3349/ymj.2015.56.5.1389-
dc.admin.authorfalse-
dc.admin.mappingfalse-
dc.contributor.localIdA02611-
dc.relation.journalcodeJ02813-
dc.identifier.eissn1976-2437-
dc.identifier.pmid26256985-
dc.subject.keywordTSH receptor autoantibody-
dc.subject.keywordTotal thyroidectomy-
dc.subject.keywordthyroid benign mass-
dc.subject.keywordthyroid cancer-
dc.subject.keywordthyroid-associated orbitopathy-
dc.contributor.alternativeNameYoon, Jin Sook-
dc.contributor.affiliatedAuthorYoon, Jin Sook-
dc.rights.accessRightsfree-
dc.citation.volume56-
dc.citation.number5-
dc.citation.startPage1389-
dc.citation.endPage1394-
dc.identifier.bibliographicCitationYONSEI MEDICAL JOURNAL, Vol.56(5) : 1389-1394, 2015-
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Ophthalmology (안과학교실) > 1. Journal Papers

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