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Left Atrial Volume Index Predicts Recurrence of Stroke in Patients with Nonsustained Atrial Tachycardia.

 Hyemoon Chung  ;  Boyoung Joung  ;  Kyung Yul Lee  ;  Jae Sun Uhm  ;  Hui Nam Pak  ;  Moon Hyoung Lee  ;  Jong Youn Kim 
 Journal of Stroke and Cerebrovascular Diseases, Vol.24(10) : 2408-2415, 2015 
Journal Title
 Journal of Stroke and Cerebrovascular Diseases 
Issue Date
BACKGROUND: Nonsustained atrial tachycardia (NSAT) is known to appear more frequently in patients with paroxysmal atrial fibrillation (AF). Enlarged left atrium (LA) is considered to be an independent risk factor for newly diagnosed AF. METHODS:We investigated the risk factors for predicting the stroke recurrence in NSAT patients. In total, 252 patients (114 women, mean 70 ± 11 years) with acute ischemic stroke and documented NSAT in 24-hour Holter monitoring were enrolled and followed. All patients underwent echo-Doppler evaluations. RESULTS: During a mean follow-up period of 35 ± 31 months, the stroke recurrence rate was 11.1% (28 of 252). The patients with recurrence (n = 28) had higher left atrium volume index (LAVI, P < .001) and higher E/e' (P = .028) compared with those without recurrence (n = 224). On the Kaplan-Meier survival analysis, stroke recurrence rate was significantly higher in patients with enlarged LA (LAVI >28 mm3/m2; P < .001 by the log-rank test), and it remained significant in multivariate analysis (hazard ratio, 1.154; 95% confidence interval [CI], 1.099-1.212, P < .001). CONCLUSIONS: In patients with acute ischemic stroke and NSAT, enlarged LA predicts an increased risk of stroke recurrence. This study supports the necessity of prolonged rhythm monitoring in stroke patients with NSAT and enlarged LA to detect undiagnosed AF and consequently considering anticoagulation therapy.
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1. Journal Papers (연구논문) > 1. College of Medicine (의과대학) > Dept. of Neurology (신경과학교실)
1. Journal Papers (연구논문) > 1. College of Medicine (의과대학) > Dept. of Internal Medicine (내과학교실)
Yonsei Authors
김종윤(Kim, Jong Youn)
박희남(Pak, Hui Nam) ORCID logo https://orcid.org/0000-0002-3256-3620
엄재선(Uhm, Jae Sun) ORCID logo https://orcid.org/0000-0002-1611-8172
이경열(Lee, Kyung Yul) ORCID logo https://orcid.org/0000-0001-5585-7739
이문형(Lee, Moon Hyoung) ORCID logo https://orcid.org/0000-0002-7268-0741
정보영(Joung, Bo Young) ORCID logo https://orcid.org/0000-0001-9036-7225
정혜문(Chung, Hye Moon)
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