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지질 치료에서 약물 병합요법

Other Titles
 Combination pharmacotherapy in lipid management 
Authors
 이상학 
Citation
 JOURNAL OF THE KOREAN MEDICAL ASSOCIATION , Vol.58(8) : 745-749, 2015 
Journal Title
 JOURNAL OF THE KOREAN MEDICAL ASSOCIATION 
ISSN
 1975-8456 
Issue Date
2015
Keywords
Ezetimibe ; Fibric acids ; Niacin ; Fatty acids, omega-3
Abstract
Latest guidelines on lipid management recommend statins as the first-line therapy. Because limited evidence is available on cardiovascular outcomes with varying statin-nonstatin combinations, recommendation levels for these regimens have been weak. However, a recent trial has demonstrated the additive effect of the statin-ezetimibe combination. The statin-fibrate combination has shown an effect in certain subgroups and on diabetic microangiopathy. Recent trials using the statin-niacin combination have been largely negative, whereas the statin-omega-3 fatty acids combination demonstrated a positive effect only in one study. Identifying the benefits and limitations of each combination is important for the best possible management of patients.
Files in This Item:
T201503376.pdf Download
DOI
10.5124/jkma.2015.58.8.745
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Internal Medicine (내과학교실) > 1. Journal Papers
Yonsei Authors
Lee, Sang Hak(이상학) ORCID logo https://orcid.org/0000-0002-4535-3745
URI
https://ir.ymlib.yonsei.ac.kr/handle/22282913/141053
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