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담도유두종 환자에서 광역학치료 후 간용적 보존 수술 1예

Other Titles
 Volume-reserving Surgery after Photodynamic Therapy for Biliary Papillomatosis: A Case Report 
 정진옥  ;  임진홍  ;  박준성  ;  박승우  ;  김현기  ;  김경식 
 Korean Journal of Gastroenterology, Vol.66(1) : 55-58, 2015 
Journal Title
 Korean Journal of Gastroenterology 
Issue Date
Biliary papillomatosis is rare, and its pathogenic mechanisms are not yet clear. Because of its high risk for malignancy transformation, surgical resection is regarded as a standard treatment. Photodynamic therapy (PDT) has been used by the intravenous administration of hematoporphyrin derivative followed by laser exposure. A photochemical process causes disturbance of the microvascular structure and degradation of membrane. Cholangitis is a major complication after PDT. A healthy 56-year-old man was diagnosed with biliary papillomatosis involving the common hepatic duct, both proximal intrahepatic bile ducts (IHD), and the right posterior IHD. After biliary decompression by endoscopic nasobiliary drainage, PDT was performed to avoid extensive liver resection and recurrence using endoscopic retrograde cholangiographic guidance. After portal vein embolization, the patient underwent extended right hemihepatectomy. Following administration of chemoradiation therapy with tegafur-uracil and 45 Gy due to local recurrence at postoperative 13 months, there was no local recurrence or distant metastases. This is the first case report on PDT for biliary papillomatosis in Korea. Preoperative PDT is beneficial for reducing the lesion in diffuse or multifocal biliary papillomatosis and may lead to curative and volume reserving surgery. Thus, PDT could improve the quality of life and prolong life expectation for biliary papillomatosis patients.
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1. Journal Papers (연구논문) > 1. College of Medicine (의과대학) > Dept. of Internal Medicine (내과학교실)
1. Journal Papers (연구논문) > 1. College of Medicine (의과대학) > Dept. of Pathology (병리학교실)
1. Journal Papers (연구논문) > 1. College of Medicine (의과대학) > Dept. of Surgery (외과학교실)
Yonsei Authors
김경식(Kim, Kyung Sik) ORCID logo https://orcid.org/0000-0001-9498-284X
김현기(Kim, Hyunki) ORCID logo https://orcid.org/0000-0003-2292-5584
박승우(Park, Seung Woo) ORCID logo https://orcid.org/0000-0001-8230-964X
박준성(Park, Joon Seong) ORCID logo https://orcid.org/0000-0001-8048-9990
임진홍(Lim, Jin Hong)
정진옥(Cheong, Chin Ock)
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