60 60

Cited 0 times in

Efficacy of Antibiotics Sprayed into Surgical Site for Prevention of the Contamination in the Spinal Surgery

Authors
 Bo-Kyung Suh  ;  Seong-Hwan Moon  ;  Tae-Hwan Kim  ;  Jae Keun Oh  ;  Yong Shin Kwon  ;  Jung-Seob Park  ;  Moon Soo Park 
Citation
 Asian Spine Journal, Vol.9(4) : 517-521, 2015 
Journal Title
 Asian Spine Journal 
ISSN
 1976-1902 
Issue Date
2015
Abstract
STUDY DESIGN: Retrospective study. PURPOSE: To evaluate the effect of intraoperative wound application of vancomycin on preventing surgical wound contamination during instrumented lumbar spinal surgery. OVERVIEW OF LITERATURE: Postoperative infection is the one of the most devastating complications of lumbar surgery. There are a few reports showing the benefits of intraoperative wound application of vancomycin during spinal surgery. However, there is no report about the effectiveness of local vancomycin instillation in prevention of surgical wound contamination. METHODS: Eighty-six patients underwent instrumented lumbar spinal surgery. Mean patient age was 65.19 years (range, 23-83 years). There were 67 females and 19 males. During surgery, vancomycin powder was applied into the surgical site before closure in 43 patients (antibiotic group) and vancomycin powder was not applied into the surgical site before closure in 43 patients (control group). The tip of the surgical drain was cultured to evaluate surgical wound contamination. Erythrocyte sedimentation rate (ESR) and C-reactive protein (CRP) were measured on the first, third, seventh, and fourteenth day after the operation. RESULTS: We found two patients with a positive culture from the tip of surgical drains in the antibiotic group, and one patient with a positive culture from the tip of the surgical drain in the control group. Postoperative ESR and CRP levels did not show significant differences between the two groups. On the third postoperative day, ESR in patients of the antibiotic group was more significantly decreased than that in patients of the control group, while CRP level did not show a significant difference between the two groups. CONCLUSIONS: There was no evidence to suggest that intraoperative vancomycin application is effective in decreasing the risk of postoperative wound infection after instrumented posterior lumbar fusion surgery.
URI
https://ir.ymlib.yonsei.ac.kr/handle/22282913/140890
DOI
10.4184/asj.2015.9.4.517
Appears in Collections:
1. Journal Papers (연구논문) > 1. College of Medicine (의과대학) > Dept. of Orthopedic Surgery (정형외과학교실)
Yonsei Authors
문성환(Moon, Seong Hwan)
사서에게 알리기
  feedback
Files in This Item:
T201503046.pdf Download
Export
RIS (EndNote)
XLS (Excel)
XML

qrcode

Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.

Browse