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Pregnancy outcomes in women with moyamoya disease: experiences at a single center in Korea

Authors
 Yun Ji Jung  ;  Min-A Kim  ;  Ja-Young Kwon  ;  Hyo Ryun Lee  ;  Hee Young Cho  ;  Yong Won Park  ;  Young Han Kim 
Citation
 Yonsei Medical Journal, Vol.56(3) : 793-797, 2015 
Journal Title
 Yonsei Medical Journal 
ISSN
 0513-5796 
Issue Date
2015
Abstract
PURPOSE: Moyamoya disease (MMD) occurs predominantly in Korean and Japanese women. The aim of this study was to investigate clinical features and pregnancy outcomes in women with MMD. MATERIALS AND METHODS: We conducted a retrospective chart review of women with MMD who visited our Department of Obstetrics and Gynecology between January 2005 and October 2013. For all study subjects, clinical features, demographic characteristics, and perinatal outcomes were recorded. RESULTS: We identified 28 pregnancies in 22 patients who had been diagnosed with MMD. The mean maternal age at delivery was 31.9±3.5 years old. The mean gestational age at delivery was 38.0±0.9 weeks. Among the 28 pregnancies, 25 (92.5%) underwent cesarean section; 19 (76.0%) of them were performed under regional anesthesia and six (24.0%) under general anesthesia. The mean newborn weight was 3233.7±348.2 g. The 5-minute Apgar score in 85% of the newborns was higher than 8, with no other apparent complications. During the puerperal period, transient ischemic attack symptom or seizure occurred in 4 cases, although patients recovered within a few days. CONCLUSION: For pregnant women with MMD, it is important to control blood pressure and prevent hyperventilation during the intrapartum period, and the best methods of delivery and anesthesia should be considered to avoid unfavorable sequelae. Additionally, a multidisciplinary approach (i.e., neurosurgery) is necessary to constantly manage underlying diseases.
Files in This Item:
T201501412.pdf Download
DOI
10.3349/ymj.2015.56.3.793
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Obstetrics and Gynecology (산부인과학교실) > 1. Journal Papers
Yonsei Authors
권자영(Kwon, Ja Young) ORCID logo https://orcid.org/0000-0003-3009-6325
김민아(Kim, Min A)
김영한(Kim, Young Han) ORCID logo https://orcid.org/0000-0003-0645-6028
박용원(Park, Yong Won)
이효련(Lee, Hyo Ryun)
정윤지(Jung, Yun Ji) ORCID logo https://orcid.org/0000-0001-6615-6401
조희영(Cho, Hee Young)
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URI
https://ir.ymlib.yonsei.ac.kr/handle/22282913/140113
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