Cited 37 times in

Mean platelet volume is elevated in patients with psoriasis vulgaris

DC Field Value Language
dc.contributor.author김대석-
dc.contributor.author김성희-
dc.contributor.author이민걸-
dc.date.accessioned2016-02-04T11:16:29Z-
dc.date.available2016-02-04T11:16:29Z-
dc.date.issued2015-
dc.identifier.issn0513-5796-
dc.identifier.urihttps://ir.ymlib.yonsei.ac.kr/handle/22282913/140059-
dc.description.abstractPURPOSE: This retrospective study was done to investigate the mean platelet volume (MPV) level in patients with psoriasis vulgaris and its relationship with disease severity. MATERIALS AND METHODS: We undertook a cross-sectional study on 176 patients and 101 healthy controls to examine the association between MPV and psoriasis. Various clinical and laboratory parameters were analyzed and compared. RESULTS: Platelet distribution width and MPV were significantly higher in patients with psoriasis than controls. In addition, there was positive correlation between Psoriasis Area Severity Index (PASI) and MPV. When psoriasis patients were grouped into mild psoriasis (PASI<10) and moderate to severe psoriasis (PASI≥10), the MPV of the latter group was significantly elevated. Nevertheless, patients with higher MPV level (MPV≥10.4 fL) did not show higher PASI than lower MPV level (MPV<10.4 fL). MPV levels significantly decreased after improvements of psoriasis with various treatments. The variations of MPV and PASI also showed significant correlation. CONCLUSION: We have shown that MPV is increased in psoriasis patients and correlates with disease severity. Therefore, MPV levels may be considered as a marker of disease severity of psoriasis.-
dc.description.statementOfResponsibilityopen-
dc.format.extent712~718-
dc.relation.isPartOfYONSEI MEDICAL JOURNAL-
dc.rightsCC BY-NC-ND 2.0 KR-
dc.rights.urihttps://creativecommons.org/licenses/by-nc-nd/2.0/kr/-
dc.subject.MESHAdult-
dc.subject.MESHBlood Sedimentation-
dc.subject.MESHCross-Sectional Studies-
dc.subject.MESHFemale-
dc.subject.MESHHumans-
dc.subject.MESHMale-
dc.subject.MESHMean Platelet Volume*-
dc.subject.MESHMiddle Aged-
dc.subject.MESHPlatelet Count-
dc.subject.MESHPsoriasis/blood*-
dc.subject.MESHPsoriasis/physiopathology*-
dc.subject.MESHRetrospective Studies-
dc.subject.MESHSeverity of Illness Index-
dc.titleMean platelet volume is elevated in patients with psoriasis vulgaris-
dc.typeArticle-
dc.contributor.collegeCollege of Medicine (의과대학)-
dc.contributor.departmentYonsei Biomedical Research Center (연세의생명연구원)-
dc.contributor.googleauthorDae Suk Kim-
dc.contributor.googleauthorJungsoo Lee-
dc.contributor.googleauthorSung Hee Kim-
dc.contributor.googleauthorSoo Min Kim-
dc.contributor.googleauthorMin-Geol Lee-
dc.identifier.doi10.3349/ymj.2015.56.3.712-
dc.admin.authorfalse-
dc.admin.mappingfalse-
dc.contributor.localIdA00366-
dc.contributor.localIdA00599-
dc.contributor.localIdA02779-
dc.relation.journalcodeJ02813-
dc.identifier.eissn1976-2437-
dc.identifier.pmid25837177-
dc.subject.keywordPsoriasis-
dc.subject.keywordmean platelet volume-
dc.subject.keywordplatelet distribution width-
dc.contributor.alternativeNameKim, Dae Suk-
dc.contributor.alternativeNameKim, Sung Hee-
dc.contributor.alternativeNameLee, Min Geol-
dc.contributor.affiliatedAuthorKim, Dae Suk-
dc.contributor.affiliatedAuthorKim, Sung Hee-
dc.contributor.affiliatedAuthorLee, Min Geol-
dc.rights.accessRightsfree-
dc.citation.volume56-
dc.citation.number3-
dc.citation.startPage712-
dc.citation.endPage718-
dc.identifier.bibliographicCitationYONSEI MEDICAL JOURNAL, Vol.56(3) : 712-718, 2015-
dc.identifier.rimsid45603-
dc.type.rimsART-
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Dermatology (피부과학교실) > 1. Journal Papers
1. College of Medicine (의과대학) > Yonsei Biomedical Research Center (연세의생명연구원) > 1. Journal Papers

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