Cited 12 times in
Analgesic effect of preoperative topical nonsteroidal antiinflammatory drugs on postoperative pain after laser-assisted subepithelial keratectomy
DC Field | Value | Language |
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dc.contributor.author | 서경률 | - |
dc.date.accessioned | 2016-02-04T11:14:17Z | - |
dc.date.available | 2016-02-04T11:14:17Z | - |
dc.date.issued | 2015 | - |
dc.identifier.issn | 0886-3350 | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/139973 | - |
dc.description.abstract | PURPOSE: To assess the effect of preoperative topical nonsteroidal antiinflammatory drugs (NSAIDs) on postoperative pain after laser-assisted subepithelial keratectomy (LASEK) and to investigate their mechanism. SETTING: Severance Eye Hospital and Saeyan Eye Clinic, Seoul, South Korea. DESIGN: Prospective randomized clinical trial. METHODS: Participants in 2 related studies were assessed. Study 1 comprised patients scheduled for bilateral LASEK (Group 1) who were randomized to receive an NSAID in 1 eye and a placebo in the fellow eye 30, 20, and 10 minutes before LASEK. Postoperative pain, glare, tearing, and irritation were assessed using a visual analog scale. Study 2 comprised healthy subjects (Group 2) who were randomly divided into subgroups. The participants in these subgroups were randomized to receive ketorolac tromethamine 0.5% in 1 eye and placebo (ofloxacin 0.3%) in the fellow eye (Group 2A), proparacaine hydrochloride 0.5% in 1 eye and placebo in the fellow eye (Group 2B), or ketorolac tromethamine 0.5% in 1 eye and placebo in the fellow eye, followed 10 minutes later by 1 drop of proparacaine hydrochloride 0.5% in both eyes (Group 2C). In all 3 groups, corneal sensitivity was measured after 1, 2, and 6 hours. RESULTS: The mean postoperative pain score in the NSAID-pretreated eye was statistically significantly lower than in the placebo-pretreated eye 6, 12, and 24 hours postoperatively (P < .05). The mean corneal sensitivity was statistically significantly lower in the NSAID-treated eye than in the placebo-treated eye at 1 and 2 hours in Groups 2A and 2C (P < .05). CONCLUSION: Preoperative administration of topical NSAIDs before LASEK effectively reduces postoperative pain. | - |
dc.description.statementOfResponsibility | open | - |
dc.format.extent | 749~755 | - |
dc.relation.isPartOf | JOURNAL OF CATARACT AND REFRACTIVE SURGERY | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.rights.uri | https://creativecommons.org/licenses/by-nc-nd/2.0/kr/ | - |
dc.subject.MESH | Administration, Topical | - |
dc.subject.MESH | Adult | - |
dc.subject.MESH | Analgesia/methods* | - |
dc.subject.MESH | Anesthetics, Local/administration & dosage | - |
dc.subject.MESH | Anti-Inflammatory Agents, Non-Steroidal/administration & dosage* | - |
dc.subject.MESH | Contrast Sensitivity/physiology | - |
dc.subject.MESH | Eye Pain/diagnosis* | - |
dc.subject.MESH | Female | - |
dc.subject.MESH | Humans | - |
dc.subject.MESH | Keratectomy, Subepithelial, Laser-Assisted/methods* | - |
dc.subject.MESH | Ketorolac Tromethamine/administration & dosage* | - |
dc.subject.MESH | Lasers, Excimer/therapeutic use | - |
dc.subject.MESH | Male | - |
dc.subject.MESH | Myopia/physiopathology | - |
dc.subject.MESH | Myopia/surgery* | - |
dc.subject.MESH | Pain Management | - |
dc.subject.MESH | Pain Measurement | - |
dc.subject.MESH | Pain, Postoperative/diagnosis* | - |
dc.subject.MESH | Preoperative Care | - |
dc.subject.MESH | Prospective Studies | - |
dc.subject.MESH | Visual Acuity/physiology | - |
dc.subject.MESH | Young Adult | - |
dc.title | Analgesic effect of preoperative topical nonsteroidal antiinflammatory drugs on postoperative pain after laser-assisted subepithelial keratectomy | - |
dc.type | Article | - |
dc.contributor.college | College of Medicine (의과대학) | - |
dc.contributor.department | Dept. of Ophthalmology (안과학) | - |
dc.contributor.googleauthor | Se Kyung Kim | - |
dc.contributor.googleauthor | Jin Pyo Hong | - |
dc.contributor.googleauthor | Sang Min Nam | - |
dc.contributor.googleauthor | Robert Doyle Stulting | - |
dc.contributor.googleauthor | Kyoung Yul Seo | - |
dc.identifier.doi | 10.1016/j.jcrs.2014.06.041 | - |
dc.admin.author | false | - |
dc.admin.mapping | false | - |
dc.contributor.localId | A01870 | - |
dc.relation.journalcode | J01299 | - |
dc.identifier.eissn | 1873-4502 | - |
dc.identifier.pmid | 25840299 | - |
dc.identifier.url | http://www.sciencedirect.com/science/article/pii/S0886335015002151 | - |
dc.contributor.alternativeName | Seo, Kyuong Yul | - |
dc.contributor.affiliatedAuthor | Seo, Kyuong Yul | - |
dc.rights.accessRights | not free | - |
dc.citation.volume | 41 | - |
dc.citation.number | 4 | - |
dc.citation.startPage | 749 | - |
dc.citation.endPage | 755 | - |
dc.identifier.bibliographicCitation | JOURNAL OF CATARACT AND REFRACTIVE SURGERY, Vol.41(4) : 749-755, 2015 | - |
dc.identifier.rimsid | 49003 | - |
dc.type.rims | ART | - |
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