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Cited 16 times in

Golgi polarization plays a role in the directional migration of neonatal dermal fibroblasts induced by the direct current electric fields

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dc.contributor.author구민아-
dc.contributor.author권병주-
dc.contributor.author김민성-
dc.contributor.author박종철-
dc.contributor.author선경미-
dc.contributor.author이미희-
dc.date.accessioned2016-02-04T11:14:05Z-
dc.date.available2016-02-04T11:14:05Z-
dc.date.issued2015-
dc.identifier.issn0006-291X-
dc.identifier.urihttps://ir.ymlib.yonsei.ac.kr/handle/22282913/139966-
dc.description.abstractDirectional cell migration requires cell polarization. The reorganization of the Golgi apparatus is an important phenomenon in the polarization and migration of many types of cells. Direct current electric fields (dc (EF) induced directional cell migration in a wide variety of cells. Here nHDFs migrated toward cathode under 1 V/cm dc EF, however 1 μM of brefeldin A (BFA) inhibited the dc EF induced directional migration. BFA (1 μM) did not cause the complete Golgi dispersal for 2 h. When the Golgi polarization maintained their direction of polarity, the direction of cell migration also kept toward the same direction of the Golgi polarization even though the dc EF was reversed. In this study, the importance of the Golgi polarization in the directional migration of nHDf under dc EF was identified.-
dc.description.statementOfResponsibilityopen-
dc.format.extent255~260-
dc.relation.isPartOfBIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS-
dc.rightsCC BY-NC-ND 2.0 KR-
dc.rights.urihttps://creativecommons.org/licenses/by-nc-nd/2.0/kr/-
dc.subject.MESHBrefeldin A/pharmacology-
dc.subject.MESHCell Movement*-
dc.subject.MESHElectricity*-
dc.subject.MESHFibroblasts/cytology-
dc.subject.MESHGolgi Apparatus/physiology*-
dc.subject.MESHHumans-
dc.subject.MESHInfant, Newborn-
dc.subject.MESHMicroscopy, Fluorescence-
dc.subject.MESHSkin/cytology*-
dc.titleGolgi polarization plays a role in the directional migration of neonatal dermal fibroblasts induced by the direct current electric fields-
dc.typeArticle-
dc.contributor.collegeCollege of Medicine (의과대학)-
dc.contributor.departmentDept. of Medical Engineering (의학공학)-
dc.contributor.googleauthorMin Sung Kim-
dc.contributor.googleauthorMi Hee Lee-
dc.contributor.googleauthorByeong-Ju Kwon-
dc.contributor.googleauthorMin-Ah Koo-
dc.contributor.googleauthorGyeung Mi Seon-
dc.contributor.googleauthorJong-Chul Park-
dc.identifier.doi10.1016/j.bbrc.2015.03.021-
dc.admin.authorfalse-
dc.admin.mappingfalse-
dc.contributor.localIdA00190-
dc.contributor.localIdA00218-
dc.contributor.localIdA01662-
dc.contributor.localIdA01932-
dc.contributor.localIdA02777-
dc.contributor.localIdA00460-
dc.relation.journalcodeJ00281-
dc.identifier.eissn1090-2104-
dc.identifier.pmid25772616-
dc.identifier.urlhttp://www.sciencedirect.com/science/article/pii/S0006291X15004568-
dc.subject.keywordDirectional migration-
dc.subject.keywordElectrotaxis-
dc.subject.keywordGalvanotaxis-
dc.subject.keywordGolgi polarization-
dc.subject.keywordNeonatal human fibroblasts-
dc.contributor.alternativeNameKoo, Min Ah-
dc.contributor.alternativeNameKwon, Byeong Ju-
dc.contributor.alternativeNameKim, Min Sung-
dc.contributor.alternativeNamePark, Jong Chul-
dc.contributor.alternativeNameSeon, Gyeung Mi-
dc.contributor.alternativeNameLee, Mi Hee-
dc.contributor.affiliatedAuthorKoo, Min Ah-
dc.contributor.affiliatedAuthorKwon, Byeong Ju-
dc.contributor.affiliatedAuthorPark, Jong Chul-
dc.contributor.affiliatedAuthorSeon, Gyeung Mi-
dc.contributor.affiliatedAuthorLee, Mi Hee-
dc.contributor.affiliatedAuthorKim, Min Sung-
dc.rights.accessRightsnot free-
dc.citation.volume460-
dc.citation.number2-
dc.citation.startPage255-
dc.citation.endPage260-
dc.identifier.bibliographicCitationBIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, Vol.460(2) : 255-260, 2015-
dc.identifier.rimsid48998-
dc.type.rimsART-
Appears in Collections:
1. College of Medicine (의과대학) > BioMedical Science Institute (의생명과학부) > 1. Journal Papers
1. College of Medicine (의과대학) > Dept. of Medical Engineering (의학공학교실) > 1. Journal Papers

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