0 318

Cited 43 times in

Modified complete mesocolic excision with central vascular ligation for the treatment of right-sided colon cancer: long-term outcomes and prognostic factors

 Cho, Min Soo  ;  Baek, Se Jin  ;  Hur, Hyuk  ;  Soh Min, Byung  ;  Baik, Seung Hyuk  ;  Kyu Kim, Nam 
 ANNALS OF SURGERY, Vol.261(4) : 708-715, 2015 
Journal Title
Issue Date
Adenocarcinoma/mortality ; Adenocarcinoma/pathology ; Adenocarcinoma/surgery* ; Chemotherapy, Adjuvant ; Colectomy/methods* ; Colonic Neoplasms/mortality ; Colonic Neoplasms/pathology ; Colonic Neoplasms/surgery* ; Comorbidity ; Conversion to Open Surgery ; Disease-Free Survival ; Female ; Gallstones/epidemiology ; Humans ; Laparoscopy/methods* ; Ligation ; Logistic Models ; Lymph Node Excision/methods ; Male ; Mesocolon/surgery* ; Middle Aged ; Multivariate Analysis ; Neoplasm Recurrence, Local/classification ; Neoplasm Staging ; Ovarian Cysts/epidemiology ; Postoperative Complications/classification ; Postoperative Complications/pathology ; Prognosis ; Retrospective Studies ; Survival Analysis ; Survival Rate ; Treatment Outcome
modified complete mesocolic excision ; oncologic outcomes ; prognostic factor ; right-sided colon cancer
OBJECTIVE: To investigate the long-term oncologic outcomes and risk factors for adverse effects in right-sided colon cancer patients who underwent modified complete mesocolic excision (mCME). BACKGROUND: Complete mesocolic excision (CME) with central vascular ligation has recently been found to improve oncological outcomes in patients with colon cancer. Our institution has established mCME on the basis of the original concept of CME for the treatment of right-sided colon cancer. METHODS: Between January 2000 and July 2009, 773 patients who underwent mCME for right-sided colon cancer were eligible for this retrospective study. The prognostic factors for survival/recurrence and the risk factors for postoperative complications were investigated. RESULTS: The mean follow-up period was 61.9 ± 34.7 months. The 5-year overall survival and 5-year disease-free survival rates were 84.0% and 82.8%, respectively. Pathologic stage III disease, postoperative complications, age more than 60 years, and minimally invasive surgery were found to be independent prognostic factors. The 5-year locoregional recurrence (LRR) and 5-year systemic recurrence rates (SRRs) were 4.9% and 13.7%, respectively. The risk of LRR and SRR increased with pathologic stage III disease. An American Society of Anesthesiology score of higher than II was an independent predictive factor of postoperative complications. CONCLUSIONS: We have successfully established the mCME technique, on the basis of the same principle as CME, but with a more tailored approach. The long-term oncologic outcomes and risk of postoperative morbidity were found to be comparable with those seen with the original CME procedure.
Full Text
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Surgery (외과학교실) > 1. Journal Papers
Yonsei Authors
Kim, Nam Kyu(김남규) ORCID logo https://orcid.org/0000-0003-0639-5632
Min, Byung Soh(민병소) ORCID logo https://orcid.org/0000-0003-0180-8565
Baek, Se Jin(백세진)
Baik, Seung Hyuk(백승혁) ORCID logo https://orcid.org/0000-0003-4183-2332
Cho, Min Soo(조민수)
Hur, Hyuk(허혁) ORCID logo https://orcid.org/0000-0002-9864-7229
사서에게 알리기


Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.