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Sex differences in the relationship between blood mercury concentration and metabolic syndrome risk

DC Field Value Language
dc.contributor.author서민석-
dc.contributor.author심재용-
dc.contributor.author이용제-
dc.date.accessioned2016-02-04T10:57:25Z-
dc.date.available2016-02-04T10:57:25Z-
dc.date.issued2015-
dc.identifier.issn0391-4097-
dc.identifier.urihttps://ir.ymlib.yonsei.ac.kr/handle/22282913/139351-
dc.description.abstractBACKGROUND: Mercury exposure enhances free radical production and reduces activity of anti-oxidant enzymes, resulting in detrimental health effects. Some researchers have reported an association between blood mercury and increased risk of metabolic syndrome (MetS); however, sex differences in the relationship were not fully considered. AIM: To examine the sex differences in the relationship between blood mercury concentration and the increased risk of MetS in Korean men and women. MATERIALS AND METHODS: A nationwide cross-sectional study was conducted to examine the relationship between blood mercury concentration and MetS in 2,976 men and 3,074 women over 19 years of age (aged 19-87 years), using data from the 2010-2012 Korean National Health and Nutrition Examination Survey (KNHANES-V). Multiple logistic regression analysis was used to assess the relationship between blood mercury concentration and the prevalence risk of MetS after adjusting for confounding variables. RESULTS: Compared to the lowest quartile of blood mercury concentration, the OR (95 % CI) for MetS of the highest quartile in men was 1.62 (1.15-2.28) after adjusting for age, smoking status, alcohol consumption, regular exercise, and BMI. Similarly, in multiple logistic regression analysis using log2-transformed blood mercury as a continuous variable, the OR (95 % CI) for having MetS with doubling of blood mercury was 1.20 (1.05-1.36) after adjusting for the same co-variables. However, the relationship was not observed in women after adjusting for the same co-variables. CONCLUSIONS: Blood mercury concentration was independently associated with an increased risk of MetS in men.-
dc.description.statementOfResponsibilityopen-
dc.relation.isPartOfJOURNAL OF ENDOCRINOLOGICAL INVESTIGATION-
dc.rightsCC BY-NC-ND 2.0 KR-
dc.rights.urihttps://creativecommons.org/licenses/by-nc-nd/2.0/kr/-
dc.subject.MESHAdult-
dc.subject.MESHBiomarkers/blood-
dc.subject.MESHCross-Sectional Studies-
dc.subject.MESHFemale-
dc.subject.MESHHumans-
dc.subject.MESHMale-
dc.subject.MESHMercury/blood*-
dc.subject.MESHMetabolic Syndrome/blood*-
dc.subject.MESHMetabolic Syndrome/diagnosis*-
dc.subject.MESHMetabolic Syndrome/epidemiology-
dc.subject.MESHMiddle Aged-
dc.subject.MESHNutrition Surveys/methods-
dc.subject.MESHRepublic of Korea/epidemiology-
dc.subject.MESHRisk Factors-
dc.subject.MESHSex Characteristics*-
dc.titleSex differences in the relationship between blood mercury concentration and metabolic syndrome risk-
dc.typeArticle-
dc.contributor.collegeCollege of Medicine (의과대학)-
dc.contributor.departmentDept. of Family Medicine (가정의학)-
dc.contributor.googleauthorJi-Youn Chung-
dc.contributor.googleauthorMin-Seok Seo-
dc.contributor.googleauthorJae-Yong Shim-
dc.contributor.googleauthorYong-Jae Lee-
dc.identifier.doi10.1007/s40618-014-0132-3-
dc.admin.authorfalse-
dc.admin.mappingfalse-
dc.contributor.localIdA01878-
dc.contributor.localIdA02207-
dc.contributor.localIdA02982-
dc.contributor.localIdA03734-
dc.relation.journalcodeJ01391-
dc.identifier.eissn1720-8386-
dc.identifier.pmid25053396-
dc.identifier.urlhttp://link.springer.com/article/10.1007%2Fs40618-014-0132-3-
dc.subject.keywordMercury-
dc.subject.keywordMetabolic syndrome-
dc.subject.keywordOxidative stress-
dc.subject.keywordSex differences-
dc.contributor.alternativeNameSeo, Min Seok-
dc.contributor.alternativeNameShim, Jae Yong-
dc.contributor.alternativeNameLee, Yong Jae-
dc.contributor.alternativeNameChung, Ji Youn-
dc.contributor.affiliatedAuthorSeo, Min Seok-
dc.contributor.affiliatedAuthorShim, Jae Yong-
dc.contributor.affiliatedAuthorLee, Yong Jae-
dc.contributor.affiliatedAuthorChung, Ji Youn-
dc.rights.accessRightsnot free-
dc.citation.volume38-
dc.citation.number1-
dc.citation.startPage65-
dc.citation.endPage71-
dc.identifier.bibliographicCitationJOURNAL OF ENDOCRINOLOGICAL INVESTIGATION, Vol.38(1) : 65-71, 2015-
dc.identifier.rimsid64955-
dc.type.rimsART-
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Family Medicine (가정의학교실) > 1. Journal Papers

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