Cited 18 times in
Sex differences in the relationship between blood mercury concentration and metabolic syndrome risk
DC Field | Value | Language |
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dc.contributor.author | 서민석 | - |
dc.contributor.author | 심재용 | - |
dc.contributor.author | 이용제 | - |
dc.date.accessioned | 2016-02-04T10:57:25Z | - |
dc.date.available | 2016-02-04T10:57:25Z | - |
dc.date.issued | 2015 | - |
dc.identifier.issn | 0391-4097 | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/139351 | - |
dc.description.abstract | BACKGROUND: Mercury exposure enhances free radical production and reduces activity of anti-oxidant enzymes, resulting in detrimental health effects. Some researchers have reported an association between blood mercury and increased risk of metabolic syndrome (MetS); however, sex differences in the relationship were not fully considered. AIM: To examine the sex differences in the relationship between blood mercury concentration and the increased risk of MetS in Korean men and women. MATERIALS AND METHODS: A nationwide cross-sectional study was conducted to examine the relationship between blood mercury concentration and MetS in 2,976 men and 3,074 women over 19 years of age (aged 19-87 years), using data from the 2010-2012 Korean National Health and Nutrition Examination Survey (KNHANES-V). Multiple logistic regression analysis was used to assess the relationship between blood mercury concentration and the prevalence risk of MetS after adjusting for confounding variables. RESULTS: Compared to the lowest quartile of blood mercury concentration, the OR (95 % CI) for MetS of the highest quartile in men was 1.62 (1.15-2.28) after adjusting for age, smoking status, alcohol consumption, regular exercise, and BMI. Similarly, in multiple logistic regression analysis using log2-transformed blood mercury as a continuous variable, the OR (95 % CI) for having MetS with doubling of blood mercury was 1.20 (1.05-1.36) after adjusting for the same co-variables. However, the relationship was not observed in women after adjusting for the same co-variables. CONCLUSIONS: Blood mercury concentration was independently associated with an increased risk of MetS in men. | - |
dc.description.statementOfResponsibility | open | - |
dc.relation.isPartOf | JOURNAL OF ENDOCRINOLOGICAL INVESTIGATION | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.rights.uri | https://creativecommons.org/licenses/by-nc-nd/2.0/kr/ | - |
dc.subject.MESH | Adult | - |
dc.subject.MESH | Biomarkers/blood | - |
dc.subject.MESH | Cross-Sectional Studies | - |
dc.subject.MESH | Female | - |
dc.subject.MESH | Humans | - |
dc.subject.MESH | Male | - |
dc.subject.MESH | Mercury/blood* | - |
dc.subject.MESH | Metabolic Syndrome/blood* | - |
dc.subject.MESH | Metabolic Syndrome/diagnosis* | - |
dc.subject.MESH | Metabolic Syndrome/epidemiology | - |
dc.subject.MESH | Middle Aged | - |
dc.subject.MESH | Nutrition Surveys/methods | - |
dc.subject.MESH | Republic of Korea/epidemiology | - |
dc.subject.MESH | Risk Factors | - |
dc.subject.MESH | Sex Characteristics* | - |
dc.title | Sex differences in the relationship between blood mercury concentration and metabolic syndrome risk | - |
dc.type | Article | - |
dc.contributor.college | College of Medicine (의과대학) | - |
dc.contributor.department | Dept. of Family Medicine (가정의학) | - |
dc.contributor.googleauthor | Ji-Youn Chung | - |
dc.contributor.googleauthor | Min-Seok Seo | - |
dc.contributor.googleauthor | Jae-Yong Shim | - |
dc.contributor.googleauthor | Yong-Jae Lee | - |
dc.identifier.doi | 10.1007/s40618-014-0132-3 | - |
dc.admin.author | false | - |
dc.admin.mapping | false | - |
dc.contributor.localId | A01878 | - |
dc.contributor.localId | A02207 | - |
dc.contributor.localId | A02982 | - |
dc.contributor.localId | A03734 | - |
dc.relation.journalcode | J01391 | - |
dc.identifier.eissn | 1720-8386 | - |
dc.identifier.pmid | 25053396 | - |
dc.identifier.url | http://link.springer.com/article/10.1007%2Fs40618-014-0132-3 | - |
dc.subject.keyword | Mercury | - |
dc.subject.keyword | Metabolic syndrome | - |
dc.subject.keyword | Oxidative stress | - |
dc.subject.keyword | Sex differences | - |
dc.contributor.alternativeName | Seo, Min Seok | - |
dc.contributor.alternativeName | Shim, Jae Yong | - |
dc.contributor.alternativeName | Lee, Yong Jae | - |
dc.contributor.alternativeName | Chung, Ji Youn | - |
dc.contributor.affiliatedAuthor | Seo, Min Seok | - |
dc.contributor.affiliatedAuthor | Shim, Jae Yong | - |
dc.contributor.affiliatedAuthor | Lee, Yong Jae | - |
dc.contributor.affiliatedAuthor | Chung, Ji Youn | - |
dc.rights.accessRights | not free | - |
dc.citation.volume | 38 | - |
dc.citation.number | 1 | - |
dc.citation.startPage | 65 | - |
dc.citation.endPage | 71 | - |
dc.identifier.bibliographicCitation | JOURNAL OF ENDOCRINOLOGICAL INVESTIGATION, Vol.38(1) : 65-71, 2015 | - |
dc.identifier.rimsid | 64955 | - |
dc.type.rims | ART | - |
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