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Neurocognitive function in children after anterior temporal lobectomy with amygdalohippocampectomy

DC FieldValueLanguage
dc.contributor.author강훈철-
dc.contributor.author김동석-
dc.contributor.author김흥동-
dc.contributor.author심규원-
dc.contributor.author엄소용-
dc.contributor.author이준수-
dc.date.accessioned2016-02-04T10:52:52Z-
dc.date.available2016-02-04T10:52:52Z-
dc.date.issued2015-
dc.identifier.issn0887-8994-
dc.identifier.urihttps://ir.ymlib.yonsei.ac.kr/handle/22282913/139184-
dc.description.abstractBACKGROUND: We assessed the postoperative neurocognitive function after temporal lobectomy in children with temporal lobe epilepsy. METHODS: This was a retrospective analysis of the data of 20 patients with Engel's class I or II outcomes after anterior temporal lobectomy with amygdalohippocampectomy between 2005 and 2008. Twenty children underwent resection of either dominant (n = 8) or nondominant (n = 12) temporal lobes, and their median age at surgery was 12.8 ± 3.2 years. We serially assessed intelligence and memory function as measured by the Korean-Wechsler Scales of Intelligence and Rey-Kim Memory test both before and after surgery. RESULTS: Intelligence quotient (IQ) and memory quotient scores remained stable during a 3.6-year median follow-up in these children after the surgery. There was no decrease of IQ or memory quotient scores in either the dominant or non-dominant hemisphere groups. Later onset of epilepsy, a shorter epilepsy duration, a smaller number of antiepileptic drugs, and postoperative seizure-free outcomes were significant good predictors of the postoperative IQ. CONCLUSION: Temporal lobectomy in children did not provoke a significant decline in intelligence or memory function. Early surgical treatment in children with intractable seizures of temporal lobe origin may result in better neurocognitive outcomes.-
dc.description.statementOfResponsibilityopen-
dc.format.extent88~93-
dc.relation.isPartOfPEDIATRIC NEUROLOGY-
dc.rightsCC BY-NC-ND 2.0 KR-
dc.rights.urihttps://creativecommons.org/licenses/by-nc-nd/2.0/kr/-
dc.subject.MESHAmygdala/surgery*-
dc.subject.MESHAnterior Temporal Lobectomy/methods*-
dc.subject.MESHChild-
dc.subject.MESHEpilepsy, Temporal Lobe/drug therapy-
dc.subject.MESHEpilepsy, Temporal Lobe/psychology*-
dc.subject.MESHEpilepsy, Temporal Lobe/surgery*-
dc.subject.MESHFemale-
dc.subject.MESHFollow-Up Studies-
dc.subject.MESHFunctional Laterality-
dc.subject.MESHHippocampus/surgery*-
dc.subject.MESHHumans-
dc.subject.MESHIntelligence-
dc.subject.MESHIntelligence Tests-
dc.subject.MESHMale-
dc.subject.MESHMemory-
dc.subject.MESHNeuropsychological Tests-
dc.subject.MESHRetrospective Studies-
dc.subject.MESHTemporal Lobe/surgery*-
dc.subject.MESHTreatment Outcome-
dc.titleNeurocognitive function in children after anterior temporal lobectomy with amygdalohippocampectomy-
dc.typeArticle-
dc.contributor.collegeCollege of Medicine (의과대학)-
dc.contributor.departmentDept. of Neurosurgery (신경외과학)-
dc.contributor.googleauthorYun-Jin Lee-
dc.contributor.googleauthorHoon-Chul Kang-
dc.contributor.googleauthorHeung Dong Kim-
dc.contributor.googleauthorDong-Seok Kim-
dc.contributor.googleauthorKyu-Won Shim-
dc.contributor.googleauthorSoyong Eom-
dc.contributor.googleauthorJoon Soo Lee-
dc.identifier.doi10.1016/j.pediatrneurol.2014.09.006-
dc.admin.authorfalse-
dc.admin.mappingfalse-
dc.contributor.localIdA00102-
dc.contributor.localIdA00402-
dc.contributor.localIdA01208-
dc.contributor.localIdA02187-
dc.contributor.localIdA03177-
dc.contributor.localIdA02334-
dc.relation.journalcodeJ02489-
dc.identifier.eissn1873-5150-
dc.identifier.pmid25439484-
dc.identifier.urlhttp://www.sciencedirect.com/science/article/pii/S088789941400575X-
dc.subject.keywordanterior temporal lobectomy-
dc.subject.keywordchild-
dc.subject.keywordintelligence-
dc.subject.keywordmemory-
dc.subject.keywordtemporal lobe epilepsy-
dc.contributor.alternativeNameKang, Hoon Chul-
dc.contributor.alternativeNameKim, Dong Seok-
dc.contributor.alternativeNameKim, Heung Dong-
dc.contributor.alternativeNameShim, Kyu Won-
dc.contributor.alternativeNameEom, So Yong-
dc.contributor.alternativeNameLee, Joon Soo-
dc.contributor.affiliatedAuthorKang, Hoon Chul-
dc.contributor.affiliatedAuthorKim, Dong Seok-
dc.contributor.affiliatedAuthorKim, Heung Dong-
dc.contributor.affiliatedAuthorShim, Kyu Won-
dc.contributor.affiliatedAuthorLee, Joon Soo-
dc.contributor.affiliatedAuthorEom, So Yong-
dc.rights.accessRightsnot free-
dc.citation.volume52-
dc.citation.number1-
dc.citation.startPage88-
dc.citation.endPage93-
dc.identifier.bibliographicCitationPEDIATRIC NEUROLOGY, Vol.52(1) : 88-93, 2015-
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Neurosurgery (신경외과학교실) > 1. Journal Papers
5. Research Institutes (연구소) > Epilepsy Research Institute (뇌전증연구소) > 1. Journal Papers
1. College of Medicine (의과대학) > Dept. of Pediatrics (소아청소년과학교실) > 1. Journal Papers

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