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Implementing a Sepsis Resuscitation Bundle Improved Clinical Outcome: A Before-and-After Study

 Jeongmin Kim  ;  Sungwon Na  ;  Young Chul Yoo  ;  Shin Ok Koh 
 Korean Journal of Critical Care Medicine, Vol.29(4) : 250-256, 2014 
Journal Title
Korean Journal of Critical Care Medicine
Issue Date
critical pathways ; education ; interdisciplinary communication ; sepsis
Background : Unlike other diseases, the management of sepsis has not been fully integrated in our daily practice. The aim of this study was to determine whether repeated training could improve compliance with a 6-h resuscitation bundle in patients with severe sepsis and septic shock.

Methods : Repeated education regarding a sepsis bundle was provided to the intensive care unit and emergency department residents, nurses, and faculties in a single university hospital. The educational program was led by a multidisciplinary team. A total of 175 adult patients with severe sepsis or septic shock were identified (88 before and 87 after the educational program). Hemodynamic resuscitation bundle and timely antibiotics administration were measured for all cases and mortality at 28 days after sepsis diagnosis was evaluated.

Results : The compliance rate for the sepsis resuscitation bundle before the educational program was poor (0%), and repeated training improved it to 80% (p < 0.001). The 28-day mortality was significantly lower in the intervention group (16% vs. 32%, p = 0.040). Within the intervention group, patients for whom the resuscitation bundle was successfully completed had a significantly lower 28-day mortality than other patients (11% vs. 41%, p = 0.004).

Conclusions : Repeated education led by a multidisciplinary team and interdisciplinary communication improved the compliance rate of the 6-h resuscitation bundle in severe sepsis and septic shock patients. Compliance with the sepsis resuscitation bundle was associated with improved 28-day mortality in the study population.
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1. College of Medicine (의과대학) > Dept. of Anesthesiology and Pain Medicine (마취통증의학교실) > 1. Journal Papers
Yonsei Authors
Koh, Shin Ok(고신옥)
Kim, Jeongmin(김정민) ORCID logo https://orcid.org/0000-0002-0468-8012
Na, Sungwon(나성원) ORCID logo https://orcid.org/0000-0002-1170-8042
Yoo, Young Chul(유영철) ORCID logo https://orcid.org/0000-0002-6334-7541
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