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Predicting Delayed Ventilator Weaning after Lung Transplantation: The Role of Body Mass Index

Authors
 Sarah Soh  ;  Jin Ha Park  ;  Jeong Min Kim  ;  Min Jung Lee  ;  Shin Ok Koh  ;  Hyo Chae Paik  ;  Moo Suk Park  ;  Sungwon Na 
Citation
 Korean Journal of Critical Care Medicine, Vol.29(4) : 273-280, 2014 
Journal Title
 Korean Journal of Critical Care Medicine 
ISSN
 2383-4870 
Issue Date
2014
Abstract
Background : Weaning from mechanical ventilation is difficult in the intensive care unit (ICU). Many controversial questions remain unanswered concerning the predictors of weaning failure. This study investigates patient characteristics and delayed weaning after lung transplantation. Methods : This study retrospectively reviewed the medical records of 17 lung transplantation patients from October 2012 to December 2013. Patients able to be weaned from mechanical ventilation within 8 days after surgery were assigned to an early group (n = 9), and the rest of the patients were assigned to the delayed group (n=8). Patients' intraoperative and postoperative characteristics were collected and analyzed, and conventional weaning predictors, including rapid shallow breathing index (RSBI), were also assessed. Results : The results of the early group showed a significantly shorter ICU stay in addition to a shorter hospitalization overall. Notably, the early group had a higher body mass index (BMI) than the delayed group (20.7 vs. 16.9, p = 0.004). In addition, reopening occurred more frequently in the delayed group (1/9 vs. 5/8, p = 0.05). During spontaneous breathing trials, tidal volume (TV) and arterial oxygen tension were significantly higher in the early group compared to the delayed weaning group, but differences in RSBI and respiratory rate (RR) between groups were not statistically significant. Conclusions : Low BMI might be associated with delayed ventilator weaning in lung transplantation patients. In addition, instead of the traditional weaning predictors of RSBI and RR, TV might be a better predictor for ventilator weaning after lung transplantation.
Files in This Item:
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DOI
10.4266/kjccm.2014.29.4.273
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Internal Medicine (내과학교실) > 1. Journal Papers
1. College of Medicine (의과대학) > Dept. of Anesthesiology and Pain Medicine (마취통증의학교실) > 1. Journal Papers
1. College of Medicine (의과대학) > Dept. of Thoracic and Cardiovascular Surgery (흉부외과학교실) > 1. Journal Papers
Yonsei Authors
Koh, Shin Ok(고신옥)
Kim, Jeongmin(김정민) ORCID logo https://orcid.org/0000-0002-0468-8012
Na, Sungwon(나성원) ORCID logo https://orcid.org/0000-0002-1170-8042
Park, Moo Suk(박무석) ORCID logo https://orcid.org/0000-0003-0820-7615
Park, Jin Ha(박진하) ORCID logo https://orcid.org/0000-0002-1398-3304
Paik, Hyo Chae(백효채) ORCID logo https://orcid.org/0000-0001-9309-8235
Soh, Sa Rah(소사라) ORCID logo https://orcid.org/0000-0001-5022-4617
Lee, Min Jeong(이민정) ORCID logo https://orcid.org/0000-0002-2712-3516
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URI
https://ir.ymlib.yonsei.ac.kr/handle/22282913/138906
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