0 193

Cited 15 times in

Prediction of malignancy with endoscopic ultrasonography in patients with branch duct-type intraductal papillary mucinous neoplasm.

 Kwang Hyuck Lee  ;  Se Joon Lee  ;  Jong Kyun Lee  ;  Ji Kon Ryu  ;  Eun Young Kim  ;  Tae Hyeon Kim  ;  Jong Ho Moon  ;  Woo Jin Lee  ;  Yu Kyung Cho  ;  Jae J. Kim 
 PANCREAS, Vol.43(8) : 1306-1311, 2014 
Journal Title
Issue Date
Adenocarcinoma, Mucinous/diagnostic imaging* ; Adenocarcinoma, Mucinous/pathology ; Adenocarcinoma, Mucinous/surgery ; Adenoma/diagnostic imaging* ; Adenoma/pathology ; Adenoma/surgery ; Aged ; Area Under Curve ; Carcinoma, Pancreatic Ductal/diagnostic imaging* ; Carcinoma, Pancreatic Ductal/pathology ; Carcinoma, Pancreatic Ductal/surgery ; Endosonography/methods* ; Female ; Humans ; Male ; Middle Aged ; Neoplasm Invasiveness ; Pancreatic Cyst/pathology ; Pancreatic Cyst/ultrastructure ; Pancreatic Ducts/diagnostic imaging ; Pancreatic Ducts/pathology ; Pancreatic Neoplasms/diagnostic imaging* ; Pancreatic Neoplasms/pathology ; Pancreatic Neoplasms/surgery ; Predictive Value of Tests ; Risk Factors
endoscopic ultrasonography ; branch duct–type intraductal papillary mucinous neoplasm ; malignancy ; diagnostic accuracy
OBJECTIVE: We evaluated the accuracy of a new endoscopic ultrasonography (EUS) scoring system to predict malignancy in branch duct-type intraductal papillary mucinous neoplasms (BD-IPMNs). METHODS: We performed a retrospective multicenter study of patients who underwent EUS within 3 months before surgery and were diagnosed as having BD-IPMNs by postoperative pathologies at 8 hospitals in Korea from August 2002 to December 2011. To predict the malignancy, we applied the EUS scoring system consisting of pancreatic cyst size, height of mural nodules, main duct dilatation, septal thickening, and patulous orifice. We evaluated the diagnostic accuracy of the new EUS scoring system and compared it with previous individual risk factors. RESULTS: Eighty-four patients (male-to-female ratio, 55:29; mean [SD] age, 64.7 [7.1] years) had 68 benign BD-IPMNs and 16 malignant intraductal papillary mucinous neoplasms. The EUS scoring system showed 75.0% sensitivity and 94.1% specificity at 7 points. This system (area under the curve, 0.939; 95% confidence interval, 0.884-0.994) resulted in a more accurate prediction than the previous known other factors including Sendai criteria, dilatation of ducts, size of the cyst, and presence of septal thickening and mural nodules. CONCLUSIONS: The EUS scoring system predicted BD-IPMN malignancy more accurately than the Sendai criteria and individual risk factors.
Full Text
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Internal Medicine (내과학교실) > 1. Journal Papers
Yonsei Authors
Lee, Se Joon(이세준) ORCID logo https://orcid.org/0000-0002-2695-2670
사서에게 알리기


Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.