298 623

Cited 6 times in

Complete Genome Sequence of the Siphoviral Bacteriophage YMC/09/04/R1988 MRSA BP: A lytic phage from a methicillin-resistant Staphylococcus aureus isolate.

DC Field Value Language
dc.contributor.author용동은-
dc.contributor.author이경원-
dc.contributor.author이양순-
dc.contributor.author전종수-
dc.contributor.author정윤섭-
dc.contributor.author최종락-
dc.contributor.author홍성극-
dc.date.accessioned2015-12-28T11:01:56Z-
dc.date.available2015-12-28T11:01:56Z-
dc.date.issued2014-
dc.identifier.issn0378-1097-
dc.identifier.urihttps://ir.ymlib.yonsei.ac.kr/handle/22282913/138546-
dc.description.abstractMethicillin-resistant Staphylococcus aureus (MRSA) is an increasing cause of serious infection, both in the community and hospital settings. Despite sophisticated strategies and efforts, the antibiotic options for treating MRSA infection have been narrowed due to the limited number of newly developed antimicrobials. Herein, we analyze the completely sequenced genome of a novel virulent phage YMC/09/04/R1988 MRSA BP as a potential alternative anti-MRSA agent, which lysed clinical isolates from a patient admitted to the hospital due to hip disarticulation. The phage contains a linear double-stranded DNA genome of 44,459 bp in length, with 33.37% GC content, 62 predicted open reading frames (ORFs), and annotated functions of only 23 ORFs that are associated with structural assembly, host lysis, DNA replication, and modification. It showed a broad host range (17 of 30 strains) against MRSA strains in clinical isolates.-
dc.description.statementOfResponsibilityopen-
dc.format.extent144~146-
dc.relation.isPartOfFEMS MICROBIOLOGY LETTERS-
dc.rightsCC BY-NC-ND 2.0 KR-
dc.rights.urihttps://creativecommons.org/licenses/by-nc-nd/2.0/kr/-
dc.titleComplete Genome Sequence of the Siphoviral Bacteriophage YMC/09/04/R1988 MRSA BP: A lytic phage from a methicillin-resistant Staphylococcus aureus isolate.-
dc.typeArticle-
dc.contributor.collegeCollege of Medicine (의과대학)-
dc.contributor.departmentYonsei Biomedical Research Center (연세의생명연구원)-
dc.contributor.googleauthorJongsoo Jeon-
dc.contributor.googleauthorRoshan D'Souza-
dc.contributor.googleauthorSung Kuk Hong-
dc.contributor.googleauthorYangsoon Lee-
dc.contributor.googleauthorDongeun Yong-
dc.contributor.googleauthorJongrak Choi-
dc.contributor.googleauthorKyungwon Lee-
dc.contributor.googleauthorYunsop Chong-
dc.identifier.doi10.1111/1574-6968.12580-
dc.admin.authorfalse-
dc.admin.mappingfalse-
dc.contributor.localIdA02423-
dc.contributor.localIdA02649-
dc.contributor.localIdA02947-
dc.contributor.localIdA03546-
dc.contributor.localIdA03679-
dc.contributor.localIdA04182-
dc.contributor.localIdA04397-
dc.relation.journalcodeJ00892-
dc.identifier.eissn1574-6968-
dc.identifier.pmid25123965-
dc.contributor.alternativeNameYong, Dong Eun-
dc.contributor.alternativeNameLee, Kyung Won-
dc.contributor.alternativeNameLee, Yang Soon-
dc.contributor.alternativeNameJeon, Jong Soo-
dc.contributor.alternativeNameChong, Yun Sop-
dc.contributor.alternativeNameChoi, Jong Rak-
dc.contributor.alternativeNameHong, Sung Kuk-
dc.contributor.affiliatedAuthorYong, Dong Eun-
dc.contributor.affiliatedAuthorLee, Kyung Won-
dc.contributor.affiliatedAuthorLee, Yang Soon-
dc.contributor.affiliatedAuthorJeon, Jong Soo-
dc.contributor.affiliatedAuthorChong, Yun Sop-
dc.contributor.affiliatedAuthorChoi, Jong Rak-
dc.contributor.affiliatedAuthorHong, Sung Kuk-
dc.citation.volume359-
dc.citation.number2-
dc.citation.startPage144-
dc.citation.endPage146-
dc.identifier.bibliographicCitationFEMS MICROBIOLOGY LETTERS, Vol.359(2) : 144-146, 2014-
dc.identifier.rimsid38374-
dc.type.rimsART-
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Laboratory Medicine (진단검사의학교실) > 1. Journal Papers
1. College of Medicine (의과대학) > Yonsei Biomedical Research Center (연세의생명연구원) > 1. Journal Papers

qrcode

Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.