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Islet Encapsulation Using Chondrocyte
DC Field | Value | Language |
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dc.contributor.author | 김유선 | - |
dc.contributor.author | 김준예 | - |
dc.contributor.author | 이재근 | - |
dc.date.accessioned | 2015-12-28T11:01:41Z | - |
dc.date.available | 2015-12-28T11:01:41Z | - |
dc.date.issued | 2014 | - |
dc.identifier.issn | 1298-1711 | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/138537 | - |
dc.description.abstract | Diabetes mellitus is one of the leading metabolic diseases that cause an increasing rate of mortality and morbidity. Recently, rather than the current drug treatment, pancreatic islet transplantation has been regarded as a potentially promising strategy for insulin- dependent diabetes mellitus while preventing complications such as kidney damage, vascular damage, nerve damage, and blindness. Recently, a number of advanced islet encapsulation techniques have been designed to enhance the efficiency of islet transplantation, including cell sheet engineering and generation of 3D islet spheroids by high density suspension system (HDSS). Chondrocytes derived from cartilage sources have been used as an encapsulation biomaterial for islets not only for autograft but also for allograft and xenograft transplantation. Cartilage is an avascular, white connective tissue that is rich in extracellular matrix, and expandable in vitro. Hence, this tissue might have immunologically privileged properties that make it an intelligent cell source for manufacture of encapsulation biomaterials. However, cell sheet engineering and HDSS still have their respective limitations, which need to be elucidated. This review will describe the advantages and disadvantages of the current encapsulation techniques in order to provide a comprehensive foundation for further modifications and improvements of tissue engineering for islet transplantation. | - |
dc.description.statementOfResponsibility | open | - |
dc.format.extent | 187~194 | - |
dc.language | Journal of the Korean Society for Transplantation | - |
dc.publisher | Journal of the Korean Society for Transplantation | - |
dc.relation.isPartOf | Journal of the Korean Society for Transplantation | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.rights.uri | https://creativecommons.org/licenses/by-nc-nd/2.0/kr/ | - |
dc.title | Islet Encapsulation Using Chondrocyte | - |
dc.type | Article | - |
dc.contributor.college | College of Medicine (의과대학) | - |
dc.contributor.department | Dept. of Surgery (외과학) | - |
dc.contributor.googleauthor | Jeong Ik Lee | - |
dc.contributor.googleauthor | Joon Ye Kim | - |
dc.contributor.googleauthor | Jae Geun Lee | - |
dc.contributor.googleauthor | Yu Seun Kim | - |
dc.identifier.doi | 10.4285/jkstn.2014.28.4.187 | - |
dc.admin.author | false | - |
dc.admin.mapping | false | - |
dc.contributor.localId | A00785 | - |
dc.contributor.localId | A00956 | - |
dc.contributor.localId | A03068 | - |
dc.relation.journalcode | J01858 | - |
dc.identifier.eissn | 2508-2604 | - |
dc.subject.keyword | Islet transplantation | - |
dc.subject.keyword | Immunoisolation | - |
dc.subject.keyword | Chondrocyte | - |
dc.subject.keyword | Encapsulation | - |
dc.contributor.alternativeName | Kim, Yu Seun | - |
dc.contributor.alternativeName | Kim, Joon Ye | - |
dc.contributor.alternativeName | Lee, Jae Geun | - |
dc.contributor.affiliatedAuthor | Kim, Yu Seun | - |
dc.contributor.affiliatedAuthor | Kim, Joon Ye | - |
dc.contributor.affiliatedAuthor | Lee, Jae Geun | - |
dc.citation.volume | 28 | - |
dc.citation.number | 4 | - |
dc.citation.startPage | 187 | - |
dc.citation.endPage | 194 | - |
dc.identifier.bibliographicCitation | Journal of the Korean Society for Transplantation, Vol.28(4) : 187-194, 2014 | - |
dc.identifier.rimsid | 38367 | - |
dc.type.rims | ART | - |
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