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Gamma Knife surgery for facial nerve schwannomas.

 Ju Hyung Moon  ;  Won Seok Chang  ;  Hyun Ho Jung  ;  Kyu Sung Lee  ;  Yong Gou Park  ;  Jong Hee Chang 
 JOURNAL OF NEUROSURGERY, Vol.121(Suppl 2) : 116-122, 2014 
Journal Title
Issue Date
Adolescent ; Adult ; Cranial Nerve Neoplasms/diagnostic imaging ; Cranial Nerve Neoplasms/surgery* ; Facial Nerve/diagnostic imaging ; Facial Nerve/physiology ; Facial Nerve/surgery* ; Female ; Follow-Up Studies ; Hearing ; Humans ; Magnetic Resonance Imaging ; Male ; Middle Aged ; Neoplasm, Residual/diagnostic imaging ; Neoplasm, Residual/surgery ; Neurilemmoma/diagnostic imaging ; Neurilemmoma/surgery* ; Radiosurgery/methods* ; Recovery of Function ; Retrospective Studies ; Tomography, X-Ray Computed ; Treatment Outcome ; Young Adult
GKS = Gamma Knife surgery ; Gamma Knife surgery ; HB = House-Brackmann ; SRS = stereotactic radiosurgery ; facial nerve ; radiosurgery ; schwannoma ; stereotactic radiosurgery
OBJECT: The aim of this study was to evaluate the tumor control rate and functional outcomes after Gamma Knife surgery (GKS) among patients with a facial nerve schwannoma.
METHODS: The authors reviewed the radiological data and clinical records for 14 patients who had consecutively undergone GKS for a facial nerve schwannoma. Before GKS, 12 patients had facial palsy, 7 patients had hearing disturbance, and 5 patients had undergone partial or subtotal tumor resection. The mean and median tumor volumes were 3707 mm(3) and 3000 mm(3), respectively (range 117-10,100 mm(3)). The mean tumor margin dose was 13.2 Gy (range 12-15 Gy), and the mean maximum tumor dose was 26.4 Gy (range 24-30 Gy). The mean follow-up period was 80.7 months (range 2-170 months).
RESULTS: Control of tumor growth was achieved in all 12 (100%) patients who were followed up for longer than 2 years. After GKS, facial nerve function improved in 2 patients, remained unchanged in 9 patients, and worsened in 3 patients. All patients who had had serviceable hearing at the preliminary examination maintained their hearing at a useful level after GKS. Other than mild tinnitus reported by 3 patients, no other major complications developed.
CONCLUSIONS: GKS for facial nerve schwannomas resulted in excellent tumor control rates and functional outcomes. GKS might be a good primary treatment option for patients with a small- to medium-sized facial nerve schwannoma when facial nerve function and hearing are relatively preserved.
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1. College of Medicine (의과대학) > Dept. of Neurosurgery (신경외과학교실) > 1. Journal Papers
Yonsei Authors
Moon, Ju Hyung(문주형)
Park, Yong Gou(박용구)
Lee, Kyu Sung(이규성)
Chang, Won Seok(장원석) ORCID logo https://orcid.org/0000-0003-3145-4016
Chang, Jong Hee(장종희) ORCID logo https://orcid.org/0000-0003-1509-9800
Jung, Hyun Ho(정현호)
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