Cited 7 times in
NT-proBNP: is it a more significant risk factor for mortality than troponin T in incident hemodialysis patients?
DC Field | Value | Language |
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dc.contributor.author | 강신욱 | - |
dc.contributor.author | 박정탁 | - |
dc.contributor.author | 오형중 | - |
dc.contributor.author | 유태현 | - |
dc.contributor.author | 이미정 | - |
dc.contributor.author | 이혜선 | - |
dc.contributor.author | 한승혁 | - |
dc.date.accessioned | 2015-12-28T10:59:43Z | - |
dc.date.available | 2015-12-28T10:59:43Z | - |
dc.date.issued | 2014 | - |
dc.identifier.issn | 0025-7974 | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/138467 | - |
dc.description.abstract | Numerous studies have demonstrated that cardiac biomarkers are significant predictors of cardiovascular (CV) and all-cause mortality in ESRD patients, but most of the studies were retrospective or included small numbers of patients, only prevalent dialysis patients, or measured 1 or 2 biomarkers. This study was to analyze the association between 3 cardiac biomarkers and mortality in incident HD patients. A prospective cohort of 864 incident HD patients was followed for 30 months. Based on the median values of baseline NT-proBNP, cTnT, and hsCRP, the patients were divided into "high" and "low" groups, and CV and all-cause mortality were compared between each group. Additionally, time-dependent ROC curves were constructed, and the NRI and IDI of the models with various biomarkers were calculated. The CV survival rates were significantly lower in the "high" NT-proBNP and cTnT groups compared to the corresponding "low" groups, while there was no significant difference in CV survival rate between the 2 hsCRP groups. However, all-cause mortality rates were significantly higher in all 3 "high" groups compared to each lower group. In multivariate analyses, only Ln NT-proBNP was found to be an independent predictor of mortality. Moreover, NT-proBNP was a more prognostic marker for mortality compared to cTnT. In conclusion, NT-proBNP is the biomarker that results in the most added prognostic value on top of traditional risk factors for CV and all-cause mortality in incident HD patients. | - |
dc.description.statementOfResponsibility | open | - |
dc.format.extent | e241~e241 | - |
dc.relation.isPartOf | MEDICINE | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.rights.uri | https://creativecommons.org/licenses/by-nc-nd/2.0/kr/ | - |
dc.subject.MESH | Adult | - |
dc.subject.MESH | Aged | - |
dc.subject.MESH | Biomarkers/blood | - |
dc.subject.MESH | Cardiovascular Diseases/blood* | - |
dc.subject.MESH | Cardiovascular Diseases/complications | - |
dc.subject.MESH | Cardiovascular Diseases/mortality | - |
dc.subject.MESH | Female | - |
dc.subject.MESH | Humans | - |
dc.subject.MESH | Kidney Failure, Chronic/blood* | - |
dc.subject.MESH | Kidney Failure, Chronic/complications | - |
dc.subject.MESH | Kidney Failure, Chronic/mortality | - |
dc.subject.MESH | Male | - |
dc.subject.MESH | Middle Aged | - |
dc.subject.MESH | Natriuretic Peptide, Brain/blood* | - |
dc.subject.MESH | Peptide Fragments/blood* | - |
dc.subject.MESH | Prospective Studies | - |
dc.subject.MESH | Renal Dialysis | - |
dc.subject.MESH | Republic of Korea/epidemiology | - |
dc.subject.MESH | Troponin T/blood* | - |
dc.title | NT-proBNP: is it a more significant risk factor for mortality than troponin T in incident hemodialysis patients? | - |
dc.type | Article | - |
dc.contributor.college | College of Medicine (의과대학) | - |
dc.contributor.department | Yonsei Biomedical Research Center (연세의생명연구원) | - |
dc.contributor.googleauthor | Hyung Jung Oh | - |
dc.contributor.googleauthor | Mi Jung Lee | - |
dc.contributor.googleauthor | Hye Sun Lee | - |
dc.contributor.googleauthor | c | - |
dc.contributor.googleauthor | Jung Tak Park | - |
dc.contributor.googleauthor | Seung Hyeok Han | - |
dc.contributor.googleauthor | Tae Hyun Yoo | - |
dc.contributor.googleauthor | Yong Lim Kim | - |
dc.contributor.googleauthor | Yon Su Kim | - |
dc.contributor.googleauthor | Chul Woo Yang | - |
dc.contributor.googleauthor | Nam Ho Kim | - |
dc.contributor.googleauthor | Shin Wook Kang | - |
dc.identifier.doi | 10.1097/MD.0000000000000241 | - |
dc.admin.author | false | - |
dc.admin.mapping | false | - |
dc.contributor.localId | A00053 | - |
dc.contributor.localId | A01654 | - |
dc.contributor.localId | A02417 | - |
dc.contributor.localId | A02526 | - |
dc.contributor.localId | A04304 | - |
dc.contributor.localId | A03312 | - |
dc.contributor.localId | A02773 | - |
dc.relation.journalcode | J02214 | - |
dc.identifier.eissn | 1536-5964 | - |
dc.identifier.pmid | 25501091 | - |
dc.contributor.alternativeName | Kang, Shin Wook | - |
dc.contributor.alternativeName | Park, Jung Tak | - |
dc.contributor.alternativeName | Oh, Hyung Jung | - |
dc.contributor.alternativeName | Yoo, Tae Hyun | - |
dc.contributor.alternativeName | Lee, Mi Jung | - |
dc.contributor.alternativeName | Lee, Hye Sun | - |
dc.contributor.alternativeName | Han, Seung Hyeok | - |
dc.contributor.affiliatedAuthor | Kang, Shin Wook | - |
dc.contributor.affiliatedAuthor | Park, Jung Tak | - |
dc.contributor.affiliatedAuthor | Oh, Hyung Jung | - |
dc.contributor.affiliatedAuthor | Yoo, Tae Hyun | - |
dc.contributor.affiliatedAuthor | Han, Seung Hyeok | - |
dc.contributor.affiliatedAuthor | Lee, Hye Sun | - |
dc.contributor.affiliatedAuthor | Lee, Mi Jung | - |
dc.citation.volume | 93 | - |
dc.citation.number | 27 | - |
dc.citation.startPage | 241 | - |
dc.identifier.bibliographicCitation | MEDICINE, Vol.93(27) : 241, 2014 | - |
dc.identifier.rimsid | 45330 | - |
dc.type.rims | ART | - |
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