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Non-invasive prediction of development of hepatocellular carcinoma using transient elastography in patients with chronic liver disease.

Authors
 Mi Sung Park  ;  Kwang Hyub Han  ;  Seung Up Kim 
Citation
 EXPERT REVIEW OF GASTROENTEROLOGY & HEPATOLOGY, Vol.8(5) : 501-511, 2014 
Journal Title
 EXPERT REVIEW OF GASTROENTEROLOGY & HEPATOLOGY 
ISSN
 1747-4124 
Issue Date
2014
MeSH
Carcinoma, Hepatocellular/etiology* ; Carcinoma, Hepatocellular/pathology ; Carcinoma, Hepatocellular/surgery ; Chronic Disease ; Decision Support Techniques* ; Disease Progression ; Elasticity ; Elasticity Imaging Techniques* ; Humans ; Liver/pathology* ; Liver Cirrhosis/complications ; Liver Cirrhosis/diagnosis* ; Liver Cirrhosis/pathology ; Liver Neoplasms/etiology* ; Liver Neoplasms/pathology ; Liver Neoplasms/surgery ; Predictive Value of Tests ; Recurrence ; Risk Assessment ; Risk Factors ; Time Factors ; Treatment Outcome
Keywords
FibroScan® ; hepatocellular carcinoma ; liver cirrhosis ; liver fibrosis ; liver stiffness ; prediction ; transient elastography
Abstract
Prognosis of patients with chronic liver disease is determined by the extent and progression of liver fibrosis, which may ultimately lead to hepatocellular carcinoma (HCC). Liver biopsy (LB) is regarded as the gold standard to estimate the extent of liver fibrosis. However, because LB has several limitations, the foremost being its invasiveness, several non-invasive methods for assessing liver fibrosis have been proposed. Of these, transient elastography (TE) provides an accurate representation of the extent of liver fibrosis. Furthermore, recent studies have focused on the usefulness of TE for assessing the risk of HCC development and HCC recurrence after curative treatment, and developed novel models to calculate the risk of HCC development based on TE findings. These issues are discussed in this expert review.
Full Text
http://www.tandfonline.com/doi/full/10.1586/17474124.2014.898563
DOI
10.1586/17474124.2014.898563
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Internal Medicine (내과학교실) > 1. Journal Papers
Yonsei Authors
Kim, Seung Up(김승업) ORCID logo https://orcid.org/0000-0002-9658-8050
Park, Mi Sung(박미성)
Han, Kwang-Hyub(한광협) ORCID logo https://orcid.org/0000-0003-3960-6539
URI
https://ir.ymlib.yonsei.ac.kr/handle/22282913/138340
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