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Serial optical coherence tomography-based observation of strut coverage on drug-eluting stent crossing side-branch vessels
DC Field | Value | Language |
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dc.contributor.author | 이승율 | - |
dc.date.accessioned | 2015-12-24T08:54:02Z | - |
dc.date.available | 2015-12-24T08:54:02Z | - |
dc.date.issued | 2013 | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/134489 | - |
dc.description | Dept. of Medicine/석사 | - |
dc.description.abstract | Serial changes in strut coverage of drug-eluting stent (DES), which are placed across side-branch vessels, remain unclear. The changes in strut coverage of DES crossing side-branch vessels (size ≥2.0 mm) were serially evaluated by optical coherence tomography (OCT) in 30 patients at 9 months and 2 years after the index DES implantation. DESs were paclitaxel-eluting stents (PESs), sirolimus-eluting stents (SESs), and zotarolimus-eluting stents (ZESs) each in 10 patients. Measured neointimal hyperplasia (NIH) thickness of 0 m on OCT was defined as an uncovered strut. The percentage of uncovered side-branch struts significantly decreased from 55.7 ± 39.9% to 36.6 ± 32.0% (p < 0.0001) on serial follow-up: PESs, 93.4 ± 10.5% to 67.6 ± 24.2%, p = 0.018; SESs, 47.5 ± 34.4% to 29.6 ± 24.1%, p = 0.036; and ZESs, 26.2 ± 34.8% to 12.4 ± 19.0%, p = 0.028. Among covered side-branch struts, the overall percentage of struts with NIH thickness more than 30 µm significantly increased from 36.3 ± 37.4% to 51.0 ± 36.0% (p < 0.0001). However, compared to other DESs, a significant increase in relatively thin NIH (0 to 30 µm) was observed in PES (1.6 ± 3.4% to 17.4 ± 16.0%, p = 0.018). Serial follow-up OCT examination showed a significant decrease in the percentage of uncovered side-branch struts, and the coverage pattern differed with DES type. | - |
dc.description.statementOfResponsibility | open | - |
dc.publisher | Graduate School, Yonsei University | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.rights.uri | https://creativecommons.org/licenses/by-nc-nd/2.0/kr/ | - |
dc.title | Serial optical coherence tomography-based observation of strut coverage on drug-eluting stent crossing side-branch vessels | - |
dc.title.alternative | 순차적 광 간섭 단층 촬영을 통한 분지 혈관 측 약물 방출 스텐트 스트럿 피복의 관찰 | - |
dc.type | Thesis | - |
dc.contributor.alternativeName | Lee, Seung Yul | - |
dc.type.local | Thesis | - |
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