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한서환경(寒署環境)이 흰쥐 취선(膵腺)에 미치는 영향에 관한 연구

Other Titles
 Effect of cold and hot environments on the exocrine pancreas of rats 
Authors
 김양선 
Issue Date
1970
Description
의학과/박사
Abstract
[한글]

[영문]

There are numerous Papers and reports concerning responses of mammals in terms of adaptation at the cellular, organ system, and whole animal level. However, it is surprisingly difficult to find information dealing with the role of gastrointestinal physiology in environmental temperature changes. In earthy Carlson (1916) has reported that exposing an animal to low external temperatures increased the tone and motility of the empty stomach. Again Sleeth and Van Liere (1937) observed that external cold accelerated the emptying of the stomach in doss whereas external heat retarded it. Other reporters (Bandes et al., 1948; Blickenstaff and Grossman, 1950) noted that gastric secretion and gastric motility are decreased in fever, even the fever is caused by an increase in environmental temperature. Recently Musacchia and Barr (1969) have observed that the absorption of glucose was

decreased in hamster following exposure to cold. The Present observations were made to determine in rats whether the functional and morphological alterations of the exocrine pancreas occurred with exposure to cold and hot environments or the

alternate condition.

Male albino rats fed 8 or 25% casein as a source of protein were exposed to cold (4-5℃) or hot(36-38℃) environment for 21 days. Another series of rats exposed alternate cold and hot environment every other days. The weight of liver, pancreas,

kidneys and testicles were increased in rats exposed to cold environment in both low and high protein regimen. The weight of spleen in hot environment and of pancreas in alternate environment were also increased in rats given high protein regimen. In rats exposed to cold the volume of biliary-pancreatic secretion was significantly increased, which may reflect the weight increase of both liver and pancreas, however, the content of amylase and lipase were decreased and trypsin was little changed or increased in case of high protein diet. In rats exposed to hat environment, in contrast, the amylase content of juice was increased in high protein regimen. Little change of pancreatic enzymes were seen in the alternate group. The serum protein of all experimental groups elevated and the serum amylase

elevated only in rats exposed to the alternate environment. The mortality of rats fed law protein diet was 33.3%in both cold and alternate environments and 25.0% in hot environment. The mortality of rats fed high protein diet was lower than low protein regimen, and furthermore, none was dead in the alternate environment in this diet.

The data indicate that exposure to either cold or hot environment bring about danger to life, and also functional and morphologic alterations of digestive viscera. The increased organ weight and digestive secretion in cold environment is suggestive of pituitary-adrenal participation in cold adaptation while no such involvement is apparent in hot adaptation. The high protein regimen demonstrated protective effect on either cold or hot environmental stress.
Full Text
https://ymlib.yonsei.ac.kr/catalog/search/book-detail/?cid=CAT000000044985
Files in This Item:
제한공개 원문입니다.
Appears in Collections:
1. College of Medicine (의과대학) > Others (기타) > 3. Dissertation
URI
https://ir.ymlib.yonsei.ac.kr/handle/22282913/126959
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