4. 흡연경력을 알 수 있었던 136예 중에서 10년 이상 흡연했던 사람이 91%를 차지하였으며 흡연과 관련이 있었던 예의 조직 유형으로는 편평상피세포암이 57%로 제일 많았다.
5. 주 증상으로는 호흡곤란이 가장 많았고 다음이 흉통, 해소 등의 순서였으며 내원시까지의 병력기간은 6개월 이내의 짧은 병력을 갖는 경우가 75%를 차지하고 있었다.
6. 우측폐가 좌측폐보다 2배 가량 폐암의 발생이 많았으며 편평상피세포암과 미분화암은 주로 폐문부와 중심부에 호발하였다.
7. 폐암으로 확진받기전 다른 질환으로 진단받아 치료를 받았던 예가 47%였다.
8. 합병증으로는 늑강내 삼출액이 제일 많았고 다음이 무기폐, 성대마비 등의 순으로 나타났다.
9. 폐암의 대다수가 경부임파선으로 전이되었다.
[영문]
Lung cancer, a rather uncommon tumor at the beginning of the century, has now become the leading cause of the death who die of malignancies. The dramatic increase in lung cancer is unique and absolute incidence almost doubled over the past 10 years.
The increase of lung cancer incidence is attributed to air pollutions by industrialization and to cigarette smoking. Korean has become rapidly industrialized during the past 15 years and the air pollution become serous public hazard.
The cigarette sale is also rapidly increasing. Thus it is suspected that the incidence of lung cancers among Koreans will naturally increase.
There has been very little comprehensive study on lung cancer among Koreans. The present study is, therefore, intended to establish a basic studies of lung cancers among Koreans form clinico-pathological aspects.
Materials and Method
The materials used in this study consisted of 287 cases of primary carcinoma of the lung for 21 year-period from 1957 to 1977.
The histopathological study was carried out by light microscopic examination using paraffin enbedding and hematozylin-eosin staining methods.
For all cases of the lung cancer, whose clinical records were available, age, sex, location, chief complaints and duration were investigated in relation to histologic types.
Result and Summary
Based on clinical and histopathological studies of 287 cases of carcinoma of the lung, following results are obtained.
1. The lung cancer has rapidly increased since early 1970th.
2. Among 287 cases, 133 cases(46.4%) were epidermoid carcinoma, 92(31.1%) were oat cell carcinoma, 34 cases(11.9%) were adenocarcinoma, 6 cases(2.1%) were bronchiolo-alveolar cell carcinoma, and 2 cases(0.7%) were bronchial adenoma.
3. The sex distribution showed male preponderance(3.9:1).
4. Among 136 cases whose smoking histories were available, 124 cases(91%) had smoked for over 10 years and 78 cases(57.4%) were epidermoid carcinoma.
5. The chief complaints were dyspnea, chest pain, coaghing and weight loss, and paraneoplastic svmtoms were observed in 2 cases.
6. The right lung showed slight preponderance(2:1).
7. Epidermoid carcinoma and oat cell carcinoma were found mostly at the hilum and central portion of both lungs.
8. Almost half(47%) of the cases had initially been treated as other benign diseases, such as pulmonary tuberculosis, common cold, bronchitis and pneumonia before confirmatory diagnosis of lumg cancer.
9. The complications were pleural effusion, atelectasis, and vocal cord paralysis in order of frequencies.
10. Almost half of the lung cancer(50.5%) had metastasized to neck lymphnodes.