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페놀 노출 근로자의 요중 페놀농도에 영향을 미치는 요인

Other Titles
 The factors that influenced urinary phenol in workers exposed to phenol 
Authors
 심규진 
Issue Date
2010
Description
산업보건학과/석사
Abstract
[한글]연구 목적: 본 연구의 목적은 페놀에 노출된 근로자의 요중 페놀에 영향을 주는 요인들의 특성을 파악하는데 있다. 연구 대상 및 방법: 본 연구는 비스페놀A 제조 공장 근로자 41명을 대상으로 연구하였으며, 작업장의 공기 중 페놀 농도와 작업 전후의 요중 페놀 농도를 측정하였으며, 요중 페놀 농도에 영향을 줄 수 있는 업무 특성과 생활습관 요인에 대한 설문조사를 실시하였다. 연구 결과: 작업자들의 작업시간 동안의 기중 페놀 농도는 0.91(불검출 ~ 2.88) mg/m3이었으며, 작업 전·후 요중 페놀 농도는 각각 100.27±75.76, 138.13±109.58 mg/g creatinine으로 통계학적으로 유의한 차이가 있었다. 흡연과 요중 페놀농도는 흡연자가 194.54±137.52 mg/g creatinine, 비흡연자가 108.88±80.10 mg/g creatinine으로 흡연자의 요중 페놀농도가 통계학적으로 유의하게 높았다 (p=0.046). 작업시간, 페놀 피부노출횟수, 음주량이가 증가 할수록 요중 페놀의 농도가 증가 하였고, 작업형태, 보호구착용여부에 따라 요중 페놀의 농도에 차이가 있었다. 다중회귀 분석을 실시한 결과 공기중 페놀농도, 작업시간, 피부노출횟수, 흡연이 통계학적으로 유의하였다. 즉, 요중 페놀농도는 흡연자가 비흡연자에 비해, 작업시간이 길어질수록 그리고 피부노출횟수가 5회 이상일 때 높아졌다. 결론: 페놀에 노출된 근로자의 요중 페놀에 영향을 주는 요인은 기중 페놀농도, 작업시간, 피부노출횟수, 흡연 및 생활습관이 요인이었다. 따라서 페놀의 노출평가를 위한 생물학적 모니터링에는 이런 요인들을 반영해야 하며, 작업장에서 피부노출 감소를 위한 노력이 필요하다.



[영문]Objectives: The purpose of this study is to identify the characteristics that affect the urinary phenol of workers exposed to phenol.

Subjects and Methods: Total 41 workers were selected at bisphenol A manufacturing plant and their urinary phenol concentration were

measured before and after work along with the phenol concentration in the workplace air, and carried out a survey on work characteristics and lifestyle factors that could affect urinary phenol.

Results: The phenol concentration in air during work hours was 0.91 (non-detection~2.88) mg/m3, and the worker’s urinary phenol concentrati ons before and after work were 100.27±75.76 and 138.13±109. 58 mg/g creatinine, respectively, which showed a statistically significant increase. Comparing smoking and urinary phenol concentration, smokers had 194.54±137.52 mg/g creatinine while non-smokers had 108.88±80.10 mg/g creatinine, thus showing the urinary phenol concentration of smokers to be statistically significantly higher (p=0.046). The urinary phenol concentration increased as work hours, the frequency of skin exposure to phenol, and the amount of drinking increased, and there

were differences in its concentration depending on the work type and whether or not workers wore protective gear.

The results of carrying out a multiple regression analysis showed that phenol concentration in air, work hours, frequency of skin exposure, and smoking were statistically significant. In other words, the urinal phenol concentration increased more for smokers than for non-smokers, when work hours became longer, and when the frequency of skin exposure was over five times.

Conclusions: The factors that influenced urinary phenol in workers exposed to phenol were phenol concentration in air, work hour, frequency of skin exposure, smoking, work and lifestyle habits.

Accordingly, biological monitoring for phenol exposure assessment must reflect these factors, and effort must be made to reduce skin exposure at workplace.
Appears in Collections:
4. Graduate School of Public Health (보건대학원) > Graduate School of Public Health (보건대학원) > 2. Thesis
URI
https://ir.ymlib.yonsei.ac.kr/handle/22282913/125090
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