Pt-Co자석이 매몰된 Hydroxyapatite Ceramics 이식체에 의한 성견 치조골 조직반응에 관한 연구

Abstract

[한글]

저자는 Pt-Co자석이 매몰된 hydroxyapatite ceramics 이식체의 의치 유지력 향상을 위한 임상적 응용가능성을 관찰하기 취하여 골과 유착되는 hydroxyapatite ceramics만으로 된 이식체를 대조군, 이식체에 자석이 매몰된 것을 실험군 Ⅰ, 이식후1 2주부터 보철물에

부착된 자석과의 상호인력 (attractive force)에 의하여 6주간 기능을 받은 이식체를 실험군Ⅱ로 하여, 각각의 시편이 이식된 5마리의 성견 치조골에서 주위조직 반응을 광학 현미경적 및 형광 현미경적으로 검경하여 다음과 같은 결론을 얻었다.

1. 대조군의 상단면은 섬유성 결체조직에 의한 피복과 일부에서는 골양조직의 형성을 보였고, 측면 및 하단면은 골조직에 의한 유착을 보였으며 국소적으로는 결체조직이 잔존되어 있었다.

2. 실험군 Ⅰ, Ⅱ에서 상단면은 섬유성 결체조직의 피복과 신생골 형성이 있고, 측면 및 하단면은 대조군과 유사한 소견을 보였다.

3. 대조군, 실험군Ⅰ, Ⅱ 모두에서 이물반응은 관찰할 수 없었다.

4. 형광 현미경적 소견상 대조군의 상단면에서 미만성의 대(band)상 또는 점(dot)상 형광과, 측면에서 동심원상의 대상 형광, 그리고 하단면에서는 감소된 대상의 형광을 보였다.

5. 형광 현미경적 소견상 실험군 Ⅰ, Ⅱ에서 상단면에 대상 및 점상형광과, 측면에서는 동심원상의 형광대를 하단면에서는 측면에 비해 현저히 감소된 형광을 보여 대조군과 유사하였다.

A STUDY OF TISSUE REACTI0NS TO Pt-Co MAGNETS EMBEDDED IN HYDROXYAPATITE CERAMIC

IMPLANTS IN THE ALVEOLAR BONE OF DOGS

Soon Ho Hong, D.D.S., M.S.D.

Department of Dental Science, The Graduate School, Yonsei University.

(Directed by Professor Ho Yong Lee, D.D.S., M.S.D., Ph. D.)

The purpose of this study is to evaluate the clinical feasibility of Pt-Co

magnets embedded in hydroxyapatite ceramic implants for the retention of dentures.

The auther investigated the tissue reactions to three groups of implants in the

alveolar bone of each dog. The hydroxyapatite ceramics without magnets were the

control group. The Pt-Co magnets embedded in hydroxyapatite ceramics were

experimental group Ⅰ. The Pt-Co magnets embedded in hydroxyapatite ceramics (as

experimental group Ⅱ) attracted the magnets attached prostheses which had been

fixed until the sacrifice of the dogs after the 12th week after implantation. 5

mongrel dogs (weighing about 15kg) were used in this study.

The tissue reactions of the three groups were observed under light microscopic

and fluorescence microscopic examination.

The results were obtained as follows:

1. In the control group, fibrous and some osteoid tissues formed on the upper

surface, and bone trabeculae were fused to the lateral and basal surface. Fibrous

tissue appeared on some parts of the basal surface.

2. In experimental group Ⅰ, Ⅱ, fibrous encapsulation and new bone formation

appeared on upper surface and findings on lateral and basal surfaces were similar

to those in the control group.

3. In control and experimental group Ⅰ, Ⅱ, no foreign body reactions were

observed.

4. On the fluorescene microscopic examination in the control group, diffuse

fluorescent bands and dots on the upper surface, and concentric fluorescent bands

on the lateral surface, as well as diminished fluorescent granules and bands on the

basal surface were observed.

5. On the fluorescence microscopic examination in experimental group Ⅰ, Ⅱ,

their findings were similar to those in the control group.

[영문]

The purpose of this study is to evaluate the clinical feasibility of Pt-Co magnets embedded in hydroxyapatite ceramic implants for the retention of dentures.

The auther investigated the tissue reactions to three groups of implants in the alveolar bone of each dog. The hydroxyapatite ceramics without magnets were the control group. The Pt-Co magnets embedded in hydroxyapatite ceramics were experimental group Ⅰ. The Pt-Co magnets embedded in hydroxyapatite ceramics (as experimental group Ⅱ) attracted the magnets attached prostheses which had been fixed until the sacrifice of the dogs after the 12th week after implantation. 5 mongrel dogs (weighing about 15kg) were used in this study.

The tissue reactions of the three groups were observed under light microscopic and fluorescence microscopic examination.

The results were obtained as follows:

1. In the control group, fibrous and some osteoid tissues formed on the upper surface, and bone trabeculae were fused to the lateral and basal surface. Fibrous tissue appeared on some parts of the basal surface.

2. In experimental group Ⅰ, Ⅱ, fibrous encapsulation and new bone formation appeared on upper surface and findings on lateral and basal surfaces were similar to those in the control group.

3. In control and experimental group Ⅰ, Ⅱ, no foreign body reactions were observed.

4. On the fluorescene microscopic examination in the control group, diffuse fluorescent bands and dots on the upper surface, and concentric fluorescent bands on the lateral surface, as well as diminished fluorescent granules and bands on the basal surface were observed.

5. On the fluorescence microscopic examination in experimental group Ⅰ, Ⅱ, their findings were similar to those in the control group.