이 연구에서 외래환자의 농에서 분리되는 가장 빈번한 세균은 s. aureus이고, 입원환자에서는 P. aeruginosa이며, 이 기간중 S.aureus와 Pseudomonas의 분리율이 약간 증가한 변화가 있었고, S.aureus는 cephalothin과 methicillin에, Enterobacteriaceae는 amikacin, gentamicin 및 tobramycin에, Pseudomonas는 amikacin에 감수성인 균주가 많다는 결론을 얻었다.
[영문]Increased incidence of nosocomial or opportunistic infections and infections due to antimicrobial resistant bacteria have been reported in recent years. Frequently isolated bacterial species may differ depending on the characteristics of hospitals. The pattern of antimicrobial susceptibility may also differ depending on the usage of antimicrobial agents.
In this study, pus culture results at the Paik Hospital Inje University medical School during January 1982 to June 1985 were analyzed. Also analyzed were the results of antimicrobial susceptibility tests.
The following results were obtained.
1. Among the 818 isolates, 41.9% were gram-positive bacteria and 58.1% gram-negative bacilli. S. aureus was the most frequently isolated gram-positive bacteria (31.3%) and P. aeruginosa the most frequently isolated gram-negative bacilli (12.2%).
2. Slightly higher annual tate of isolation was noted for S. marcescens in 1982 and for S. aureus and Pseudomonas in 1985. Rest of the species showed similar rates.
3. S. aureus showed the lowest isolation rate in November-December, and P. aeruginosa the highest rate in September-October.
4. S. aureus was more frequently isolated from outpatients and of P. aeruginosa from inpatients.
5. Most of the S. aereus isolates were susceptible to cephalothin (87.%) and methicillin (81%).
6. Most of the Enterobacteriaceae isolates were susceptible to amikacin, gentamicin and tobramycin, while many of them were resistant to ampicillin.
7. Only 48% and 53% of Pseudomonas isolates were susceptible to gentamicin and tobramycin respectively, while 86% were susceptible to amikacin.
It is concluded that moat frequently isolated species of bacteria are S. aureus from outpatients and P. aeruginosa from inpatients, frequency of isolation of S. aureus and Pseudomonas increased slightly during this period, and that most isolates of S. aureus is susceptible to cephalothin and methicillin,
Enterobacteriaceae to amikacin, gentamicin and tobramycin, and Pseudomonas to amikacin.